Cancer cytogenetics : methods and protocols
著者
書誌事項
Cancer cytogenetics : methods and protocols
（Methods in molecular biology / John M. Walker, series editor, v. 220）
Humana Press, c2003
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This is a collection of key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies. The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias towards anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH.
目次
Introduction John Swansbury Cytogenetic Studies in Hematologic Malignancies: An Overview John Swansbury The Myeloid Disorders: Background John Swansbury Cytogenetic Techniques for Myeloid Disorders John Swansbury Acute Lymphoblastic Leukemia: Background John Swansbury Conventional Cytogenetic Techniques in the Diagnosis of Childhood Acute Lymphoblastic Leukemia Susana C. Raimondi and Susan Mathew Chromosome Preparations from Bone Marrow in Acute Lymphoblastic Leukemia: Cytogenetic Techniques Ann Watmore Lymphoid Disorders Other than Common Acute Lymphoblastic Leukemia: Background John Swansbury Other Lymphoid Malignancies: Cytogenetic Techniques John Swansbury Cytogenetic and Genetic Studies in Solid Tumors: Background John Swansbury Human Solid Tumors: Cytogenetic Techniques Pietro Polito, Paola Dal Cin, Maria Debiec-Rychter, and Anne Hagemeijer Analysis and Interpretation of Cytogenetic Findings in Malignancies John Swansbury Cytogenetic Studies Using FISH: Background Toon Min and John Swansbury FISH Techniques Toon Min FISH, CGH, and SKY in the Diagnosis of Childhood Acute Lymphoblastic Leukemia Susan Mathew and Susana C. Raimondi Solving Problems in Multiplex FISH Jon C. Strefford Some Difficult Choices in Cytogenetics John Swansbury Introduction to the Analysis of the Human G-Banded Karyotype John Swansbury Index About the Authors
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