Oral tolerance : the response of the intestinal mucosa to dietary antigens
Author(s)
Bibliographic Information
Oral tolerance : the response of the intestinal mucosa to dietary antigens
(Medical intelligence unit)
Landes Bioscience/Eurekah.com, c2004
Available at 2 libraries
  Aomori
  Iwate
  Miyagi
  Akita
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  Toyama
  Ishikawa
  Fukui
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  Gifu
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  Kyoto
  Osaka
  Hyogo
  Nara
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  Tottori
  Shimane
  Okayama
  Hiroshima
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  Tokushima
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  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
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  United Kingdom
  Germany
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Oral tolerance is a major immunological property of the gastrointestinal mucosa. It plays a critical role in immune defence by preventing inflammatory and allergic responses to dietary and non pathogenic microbial antigens. The interest in oral tolerance has been renewed in the recent years, due to novel insights on its cellular mechanisms and potential clinical applications in the treatment of autoimmune diseases.
Oral Tolerance: Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential, has been designed as a concise yet comprehensive overview of the newest fundamental and clinical advances in the field. Based on the outstanding contribution of world experts, this book will be helpful to students, clinicians, and researchers working in mucosal immunology and gastroenterology.
The first part of this volume describes the structure and functions of the gastrointestinal mucosa and the fundamental features and mechanisms of oral tolerance, including the role of T cells, cytokines, IgA antibodies, and bacterial antigens. The second part explores the clinical implications of the disruption of oral tolerance in Inflammatory Bowel Diseases, food and milk allergies, and coeliac disease in particular. The final chapter focuses on the clinical potential of oral tolerance as a promising therapeutic tool.
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