Human Brain Proteome
著者
書誌事項
Human Brain Proteome
(International review of neurobiology, v. 61)
Academic Press, c2004
大学図書館所蔵 全10件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Proteomics is a systematic approach for studying the identity and function of all proteins expressed in a cell, tissue or organ. New drug targets for diseases are often identified by comparing the proteome of the disease state to the normal state. As a result, proteomics has become increasingly important in the pharmaceutical and biotechnology industries as well as academics. This book contains five sections encompassing the research aspects of proteomics on the brain including the most recent advances in the technology and informatics. It discusses advances in high-throughput proteomic technologies and their application to studying neurological disorders such as Alzheimer's disease, alcoholism, trauma/stroke, Huntington's disease, and Parkinson's disease. With numerous illustrations to explain the concepts, it provides a comprehensive review on the topic. This book: describes the latest databases and techniques for analyzing the data generated by proteomics; outlines the latest developments in proteomic methods; and, provides numerous color illustrations highlighting the application of proteomics to the identification of novel drug targets and biomarkers.
目次
Section I: High-Throughput Technologies Biomarker Discovery Using Molecular Profiling Approaches Proteomic Analysis of Mitochondrial Proteins Section II: Proteomic Applications NMDA Receptors, Neural Pathways and Protein Interaction Databases Dopamine Transporter Networks and Pathways Proteomic Approaches in Drug Discovery and Development Section III: Informatics Proteomic Informatics Proteomics Analysis in Alzheimer's Disease: New Insights into Mechanisms of Neurodegeneration Proteomics and Alcoholism Proteomic Studies of Traumatic Brain Injury Influence of Huntington's Disease on the Human and Mouse Proteome Section V: Overview of the Neuroproteome Proteomics - Application to the Brain
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