Non-myeloablative allogeneic transplantation
著者
書誌事項
Non-myeloablative allogeneic transplantation
(Cancer treatment and research)
Kluwer Academic Publishers, c2002
大学図書館所蔵 全3件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic therapy to prepare patients for allografting of hematopoietic stem cells and lymphocytes. It has the potential to deliver the potent anti-tumor immunotherapy and bone marrow replacement capacity of allogeneic stem cell transplantation to patients with reduced treatment-related morbidity and mortality. It may also enable allogeneic transplantation in patients who would be considered ineligible for conventional transplants because of co-morbidity or advanced age. However, this approach may necessitate more careful monitoring of post-transplant chimerism and malignant disease-status than is usual with conventional allografting. There is also controversy regarding the best preparative regimen and graft-versus-host disease prophylaxis to use.
目次
- Contributors. Preface. 1. Development of allogeneic hematopoietic stem cell transplantation (HSCT)
- J. Castro, E.D. Ball. 2. Immunosuppression with limited toxicity: characteristics of nucleoside analogs and anti-lymphocyte antibodies used in non-myeloablative hematopoietic cell transplantation
- A. Bashey. 3. Mobilization of allogeneic peripheral blood progenitor cells
- P. Law, T. Lane. 4. Non-myeloblative induction of mixed hematopoietic chimerism: application to transplantation tolerance and hematologic malignancies in experimental and clinical studies
- M. Sykes, T. Spitzer. 5. Combined use of autografting and non-myeloablative allografting for the treatment of hematologic malignancies and metastatic breast cancer
- A.M. Carella, E. Lerma, M. Cavaliere, M.T. Corsetti. 6. Non-myeloablative hematopoietic stem cell transplantation (NHT) in the treatment of human malignancies: from animal models to clinical practice
- A. Shimoni, A. Nagler. 7. Non-myeloablative allogeneic hematopoietic transplantation and induction of graft-versus-malignancy
- I. Khouri, S. Giralt, R. Champlin. 8. Outpatient allografting in hematologic malignancies and nonmalignant disorders - applying lessons learned in the canine model to humans
- M. Maris, R.F. Storb. 9. Non-myeloablative transplants for congenital diseases
- J. Donahue, E. Carrier. Index.
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