Ultrathin electrochemical chemo- and biosensors : technology and performance
著者
書誌事項
Ultrathin electrochemical chemo- and biosensors : technology and performance
(Springer series on chemical sensors and biosensors : methods and applications / Otto S. Wolfbeis series editor, 2)
Springer, c2004
大学図書館所蔵 全4件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Traditional biological sensors, based on enzymatic receptors and potentiometric or amperometric transducers are well reviewed and are nowadays even included extensively in many textbooks. The editors of this volume, the 2nd in the new Springer Series on Chemical and Biosensors, have focussed exclusively on alternative types of chemical and biological sensors or sensor-like structures. Special attention is given to sensor principles based on the use of linear or non-linear impedance spectroscopy.
After self-assembled monolayers have become a viable technology for the immobilization of organic molecules on electrodes and for the formation of covalently stabilized receptor layers and even more sophisticated organic nano- and microstructures, this has led to the development of numerous analytical applications of impedometric sensor methods. These new and very promising types of sensors, their technology and performance in real world applications form the main topic of this book written by leading experts from around the world.
目次
Ultrathin Electrochemical Chemo- and Biosensors: Technology and Performance Contents Preface Part 1: Receptors Antibodies for biosensors K. Kramer and B. Hock Technical University of Muenchen, Center of Life Sciences, Chair of Cell Biology, Alte Akademie 12, D-85350 Freising, Germany 1. Introduction 2. Structure and function of antibodies 3. Production of antibodies 3.1. Antibodies obtained from sera and hybridoma cell cultures 3.2. Recombinant antibodies 3.3. Antibody library derived from a set of B cells 4. Diversification by chain shuffling 5. Antibody optimization as special case of genetic algorithms 6. Biosensors as tool in evolutionary antibody synthesis 6.1. Antibodies as receptors in biosensor designs 6.2. Limitations of antibody based biosensor designs 7. Conclusions and outlook Molecularly imprinted polymers as recognition elements in sensors Karsten Haupt University of Technology of Compiegne, B.P. 20529, 60205 Compiegne cedex, France 1. Molecularly imprinted polymers 1.1. General principle of molecular imprinting 1.2. The imprinting matrix 1.2.1. Acrylic and vinyl polymers 1.2.2. Other organic polymers 1.2.3. Other imprinting matrices 1.3. Target molecules 1.4. Physical forms and preparation methods of MIPs 1.4.1. Imprinted particles - making MIPs smaller 1.4.2. Imprinting at surfaces 1.4.3. Thin imprinted polymer films 2. Applications of imprinted polymers in sensors 2.1. General considerations 2.2. General transducer types 2.3. The analyte generates the signal 2.4. The polymer generates the signal 3. Outlook Part 2. Impedometric and amperometric chemical and biologicalsensors Capacitance Affinity Biosensors Helen Berney National Microelectronics Research Centre, Prospect Row, Lee Maltings Cork, Ireland. 1 Introduction 2 Capacitance Based Transduction 2.1 The Electrode-Electrolyte Interface 2.1.1 Metal Electrodes 2.1.2 Semiconductor Electrodes 2.2 Modelling the Electrode-Electrolyte Interface 3 Capacitance Sensors 3.1 Capacitance Sensing with Interdigitated Electrodes 3.2 Capacitance Sensing at the Metal/Solution Interface 3.3 Capacitance Sensing at the Semiconductor/Solution Interface 4 Conclusions References Immunosensors and DNA-Sensors Based on Impedance Spectroscopy Eugenii Katz and Itamar Willner Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel 1. Introduction. 2. Impedance Spectroscopy - Theoretical Background. 3. Immunosensors Based on Impedance Spectroscopy. 3.1. Immunosensors based on in-plane impedance measurements between electrodes. 3.2. Immunosensors based on interfacial impedance measurements at electrodes. 4. DNA Sensors Based on Impedance Spectroscopy. 4.1. Impedimetric sensing of DNA hybridization. 4.2. Impedimetric sensing of single-base mismatches in DNA sequences. 4.3. Impedimetric sensing of DNA and RNA replication. 5. Conclusions and Perspectives. 'Voltohmmetry' - a new transducer principle for electrochemical sensors Michael J. Schoening University of Applied Sciences Aachen (Division Julich) and Institute of Thin Films and Interfaces (Research Centre Julich), D-52425 Julich, Germany 1. Introduction 2. Theory and experiment 2.1 Theory of surface resistance change 2.2 Fabrication of thin-film electrodes 2.3 Instrumentation and chemicals 2.4
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