Pioneering stem cell/gene therapy trials

著者

書誌事項

Pioneering stem cell/gene therapy trials

editors, Roger Bertolotti, Keiya Ozawa and H. Kirk Hammond

(Progress in gene therapy, v. 2)

VSP, 2004

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene therapy or emerging autologous stem cell transplantation. Highlights also include 1) promises of the breakthrough combination of stem cell- and transient gene-therapy, 2) gene therapy trials for neurodegenerative disease on non-human primates where long-term gene therapy might involve brain stem cells, and 3) the first clinical trial with non-invasive monitoring of therapeutic gene expression as a prospective conclusion. This volume will be of value and interest to researchers in this exciting field.

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