Bacterial virulence factors and Rho GTPases

Bibliographic Information

Bacterial virulence factors and Rho GTPases

P. Boquet, E. Lemichez (eds.)

(Current topics in microbiology and immunology, v. 291)

Springer, 2005

Available at  / 10 libraries

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Description and Table of Contents

Description

Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The authors in this volume show a synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfil their virulence.

Table of Contents

Foreword.- Bacterial Virulence strategies that utilize Rho GTPases.- Extracellular bacterial pathogens and small GTPases of the Rho family, an unexpected combination.- Triggered phagocytosis by Salmonella: bacterial molecular mimicry of Rho GTPase activation/deactivation.- Regulation of actin dynamics during phagocytosis by Rho GTPases.- The immunological synapse and Rho GTPases.- Rho GTPases and the control of the oxidative burst in polymorphonuclear leukocytes.- Clostridial Rho-inhibiting protein toxins.- The type III cytotoxins of yersinia and pseudomonas aeruginosa that modulate the actin cytoskeleton.- Subject index

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