Transglutaminases : family of enzymes with diverse functions

著者

    • Mehta, Kapil, Dr
    • Eckert, Richard (Richard L.)

書誌事項

Transglutaminases : family of enzymes with diverse functions

volume editors, Kapil Mehta, Richard Eckert

（Progress in experimental tumor research, v. 38）

Karger, c2005

大学図書館所蔵 件 / 全4件

この図書・雑誌をさがす

注記

Includes bibliographical references and index

HTTP:URL=http://www.loc.gov/catdir/toc/ecip055/2004029529.html Information=Table of contents

収録内容

  • Mammalian transglutaminases : a family portrait / Mehta, K.
  • Structure-function relationships of transglutaminases, a contemporary view / Nemes, Z., Csosz, E., Fesus, L.
  • Transglutaminases and their substrates / Facchiano, F., Facchiano, A.
  • Type 2 transglutaminase and cell death / Piacentini, M. ... [et al.]
  • Transglutaminase and cell-survival signaling / Singh, U.S., Pan, J.
  • Transglutaminases in wound healing and inflammation / Verderio, E.A.M., Johnson, T.S., Griffin, M.
  • Transglutaminases in epidermis / Eckert, R.L. ... [et al.]
  • Tissue transglutaminase (TG2) in cancer biology / Mangala, L.S., Mehta, K.
  • Transglutaminases in neurodegenerative disorders / Bailey, C.D.C., Tucholski, J., Johnson, G.V.W.
  • Tissue transglutaminase and celiac disease / Esposito, C. ... [et al.]
  • Transglutaminases as biotechnological tools / Mariniello, L., Porta, R.
  • Extracellular transglutaminase: factor XIII / Ichinose, A.
  • Transglutaminases of lower organisms / Rao, R.U., Chandrashekar, R., Mehta, K.
  • Transglutaminases of higher, lower plants and fungi / Del Duca, S., Serafini-Fracassini, D

内容説明・目次

内容説明

Transglutaminases are a family of structurally and functionally related enzymes that are widely distributed and have been identified in a variety of organisms ranging from bacteria to mammals and plants. The reactions (isopeptide bonds) catalyzed by these enzymes are of great physiologic significance; they are highly stable and resistant to proteolytic degradation. Isopeptide bonds are commonly found in hair and skin, and they accumulate during wound healing, apoptosis, and blood clotting. Dysregulation of transglutaminase functions results in a number of pathologic conditions, such as neurodegeneration, autoimmune diseases, infectious diseases, progressive tissue fibrosis and diseases related to the assembly of the stratum corneum of the epidermis of the skin. The ability of transglutaminases to catalyze highly stable isopeptide bonds is also being exploited by the food processing and textile industries. Moreover, there has been a recent surge in findings indicating that transglutaminases are involved in various biological processes such as normal and neoplastic cell growth, reproduction, and cell death. As newer members of the transglutaminase family are being discovered and new functions for existing members are being described, it becomes imperative to collect all the findings in a book. This volume provides the most comprehensive single source of information and will appeal to both new investigators just entering the field and established researchers aiming to elucidate the biological relevance of these enzymes in cancer, inflammation, autoimmune diseases and related areas of research.

目次

  • Preface Mammalian Transglutaminases: A Family Portrait: Mehta, K. Structure-Function Relationships of Transglutaminases - A Contemporary View: Nemes, Z.: Csosz, E.
  • Petrovskl, G.
  • Fesus, L. Transglutaminases and Their Substrates: Facchlano, F.
  • Facchiano, A. Type 2 Transglutaminase and Cell Death: Placentinl, M.
  • Amendola, A.
  • Ciccosanti, F.
  • Falasca, L.
  • Farrace, M.G.
  • Mastroberardino, P.G.
  • Nardacci, R.
  • Oliverio, S.
  • Piredda, L.
  • Rodolfo, C.
  • Autuori, F. Transglutaminase and Cell-Survival Signaling: Singh, U.S.
  • Pan, J. Transglutaminases in Wound Healing and Inflammation: Verderio, E.A.M.
  • Johnson, T.S.
  • Griffin, M. Transglutaminases in Epidermis: Eckert, R.L.
  • Sturniolo, M.T.
  • Broome, A.-M.
  • Ruse, M.
  • Rorke, E.A. Tissue Transglutaminase (TG2) in Cancer Biology: Mangala, L.S.
  • Mehta, K. Transglutaminases in Neurodegenerative Disorders: Bailey, C.D.C.
  • Tucholski, J.
  • Johnson, G.V.W. Tissue Transglutaminase and Celiac Disease: Esposito, C.
  • Caputo, I.
  • Auricchio, S.
  • Troncone, R. Transglutaminases as Biotechnological Tools: Mariniello, L.
  • Porta, R. Extracellular Transglutaminase: Factor XIII: Ichinose, A. Transglutaminases of Lower Organisms: Rao, R.U.
  • Chandrashekar, R.
  • Mehta, K. Transglutaminases of Higher, Lower Plants and Fungi: Del Duca, S.
  • Serafini-Fracassini, D. Author Index Subject Index

「Nielsen BookData」 より

関連文献： 1件中  1-1を表示

詳細情報

ページトップへ