Vitamin D and rickets
Author(s)
Bibliographic Information
Vitamin D and rickets
(Endocrine development / editor, M. O. Savage, v.6)
Karger, c2003
- : hbk : alk paper
Available at 3 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Includes bibliographical references and index
ISSN:1421-7082
Description and Table of Contents
Description
Centuries ago, during the industrial revolution, rickets, also called 'the English disease', spread rapidly among city-dwelling poor children and became endemic due to vitamin D deficiency and insufficient access to sunlight. Nowadays it appears to be endemic again as the increase of vitamin D deficiency is paralleling the primacy of breast-feeding in Western societies. Breastfeeding, nutritional status and dark skin are the main risk factors for rickets or 'rachitis' as is the correct medical term. Rickets is a childhood disorder and the basis for understanding the disease is rooted in the concept of mineral metabolism and its control mechanisms in the growing fetus, infant and child. As it is now understood that rickets is not only caused by vitamin D deficiency, it has to be kept in mind that vitamin D and calcium deficiency is prevalent in developing countries as well as in affluent societies, where children and their mothers are not exposed to as much sunlight as they need. The rapid growth in molecular biology has been exemplified in the application of subcellular technologies to study vitamin D in human and animal models. In this volume the latest research on vitamin D and rickets is presented from different perspectives such as the interesting historical overview to bone metabolism, molecular genetics of vitamin D and conclusions for disease prevention. It will be of special interest to pediatricians, endocrinologists and health care specialists who work with children at risk for the disease.
Table of Contents
- Normal mineral homeostasis
- interplay of parathyroid hormone and vitamin D, Levine, M.A.
- maternal, fetal and neonatal vitamin D and calcium metabolism during pregnancy and lactation, Weisman, Y.
- Vitamin D Receptor, Yamada, S., Shimizu, M., Yamamoto, K.
- the rachitic bone, Rauch, F.
- imaging of rachitic bone, States, L.J.
- vitamin D deficiency rickets, Shaw, N.J. calcium-deficiency rickets, Thacher, T.D.
- hypophosphatemic rickets, Drezner, M.K.
- vitamin D biosynthesis and vitamin D 1a-hydroxylase deficiency, Miller, W.L., Portale, A.A.
- hereditary 1,25-dihydroxyvitamin D-resistant rickets, Malloy, P.J.
- Feldman, D.
- rickets in transgenic animals, Carmeliet, G., Van Cromphaut, S., Maes, C., Raemaekers, T., Bouillon, R.
- rickets in developing countries, Bereket, A.
- prophylactic vitamin D supplementation, Calikoglu, A.S., Davenport, M.L.
- consensus development for the supplementation of vitamin D in childhood and adolescence, Hochberg, Z. et al.
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