Hematopoietic stem cells
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Bibliographic Information
Hematopoietic stem cells
（Annals of the New York Academy of Sciences, v. 1044,
New York Academy of Sciences, c2005-
- 5: cloth
- 5: paper
- 6: paper
- 7: paper
- Other Title
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Hematopoietic stem cells V
Hematopoietic stem cells VI
Hematopoietic stem cells VII
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6-: Publiser changed to Blackwell Pub. on behalf of the New York Academy of Sciences (Boston, Mass.)
5 : "This volume is the result of a conference entitled Hematopoietic Stem Cells V, held on September 16-18, 2004 in Tubingen, Germany."
6 : "This volume is the result of a conference entitled Sixth International Symposium and Workshop on Hematopoietic Stem Cells, held on September 14-16, 2006, in Tubingen, Germany."
7: This volume presents manuscripts stemming from the conference entitled "Hematopoietic stem cells VII," held in Meersburg, Lake Constance, Germany on September 18-20, 2008.--contents p.
Includes bibliographical references and index
Description and Table of Contents
- Volume
-
5: paper ISBN 9781573315890
Description
The most recent developments in hematopoietic stem cell research are presented in this volume, along with their clinical implications. The field of hematopoietic stem cell biology is rapidly advancing, and new ideas and concepts supported by fascinating new technologies captivated the interest and excitement of the participants of the meeting.
The sharing of new ideas and technologies with other scientists represents an invaluable stimulus, particularly for the young investigators in the field. It is hoped that the spirit of the meeting will be carried forward to the readers of this volume and that its content will stimulate new and fruitful projects in the field of stem cell biology.
The major topics covered are genetic and epigenetic regulation of stem cells, stem cell plasticity, stem cell regulation and self-renewal, and embryonic stem cells as well as malignant stem cell biology.
NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.
ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Table of Contents
Introduction: Donald Orlic, Katja C. Weisel, Willem E. Fibbe, and Lothar Kanz. .
Part I: Malignant Hematopoiesis:.
1. Acute Myeloid Leukemia Stem Cells: John E. Dick.
2. Control of Self-Renewal and Differentiation of Hematopoietic Stem Cells: HOXB4 on the Threshold: Hannes Klump, Bernhard Schiedlmeier, and Christopher Baum.
3. Developmental Impact of Leukemic Fusion Genes on Stem Cell Fate: Tariq Enver, Shinobu Tsuzuki, John Brown, Dengli Hong, Rajeev Gupta, Tony Ford, Minenori-Ishimae Egucchi, Mariko Egucchi, and Mel Greaves.
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Part II: Early Hematopoiesis:.
4. Derivation of the Hematopoietic Stem Cell Compartment from Human Embryonic Stem Cell Lines: Mickie Bhatia.
5. Thrombopoietin Regulates Differentiation of Rhesus Monkey Embryonic Stem Cells to Hematopoietic Cells: Zheng Wang, Julia Skokowa, andri Pramono, Matthias Ballmaier, and Karl Welte.
6. The Vascular Wall as a Source of Stem Cells: Manuela Tavian, Bo Zheng, Estelle Oberlin, Mihaela Crisan, Bin Sun, Johnny Huard, and Bruno Peault.
7. Genetic and Functional Characterization of Isolated Stromal Cell Lines from the Aorta-Gonado-Mesonephros Region: Katja C. Weisel and Malcolm A. S. Moore.
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Part III: Mobilization:.
8. Involvement of Proteases in Cytokine-Induced Hematopoietic Stem Cell Mobilization: Gerjo A. Velders and Willem E. Fibbe.
7. Hematopoietic Stem Cell Transplantation across Major Genetic Barriers: Tolerance Induction by Megadose CD34 Cells and Other Veto Cells: Yair Reisner, Hilit Gur, Shlomit Reich-Zeliger, Massimo F. Martelli, and Esther Bachar-Lustig.
8. The Role of Sphingosine 1-Phosphate Receptors in the Trafficking of Hematopoietic Progenitor Cells: Gabriele Seitz, andreas M. Boehmler, Lothar Kanz, and Robert Moehle.
.
Part IV: Gene Expression in Stem Cells:.
9. Epigenetic Regulation of Normal and Cancer Stem Cells: Michael F. Clarke.
10. Distinct Gene Expression Pattern of Malignant Hematopoietic Stem and Progenitor Cells in Polycythemia Vera: Ulrich Steidl, Thomas Schroeder, Christian Steidl, Guido Kobbe, Thorsten Graef, Simone Bork, Sabrina Pechtel, Slawomir Kliszewski, andrea Kuendgen, Ulrich P. Rohr, Roland Fenk, Michael Schroeder, Detlef Haase, Rainer Haas, and Ralf Kronenwett.
11. Hox Genes: From Leukemia to Hematopoietic Stem Cell Expansion: Carolina Abramovich, Nicolas Pineault, Hideaki Ohta, and R Keith Humphries.
Part V: Plasticity:.
12. Engraftment of Bone Marrow-Derived Epithelial Cells: Diane S. Krause.
13. Lineage Promiscuity and Plasticity in Hematopoietic Development: Koichi Akashi.
14. Stem Cell Biology: A View toward the Future: Ihor R. Lemischka.
Part VI: Regulators:.
15. Thrombopoietin and the Hematopoietic Stem Cell: Kenneth Kaushansky.
16. Role of GATA-1 in Normal and Neoplastic Hemopoiesis: Anna Rita Migliaccio, Rosa Alba Rana, Alessandro M. Vannucchi, and Francesco A. Manzoli.
17. Gene Expression in Stem Cell-Supporting Stromal Cell Lines: Pierre Charbord and Kateri Moore.
18. Effect of Tyrosine Kinase Inhibition Using Imatinib on Normal Lymphohematopoietic Cells: Stefan Balabanov, Silke Appel, Lothar Kanz, Peter Brossart, and Tim H. Brummendorf.
Part VII: Clonality:.
19. Stem Cell Gene Transfer: Insights into Integration and Hematopoiesis from Primate Genetic Marking Studies: Cynthia E. Dunbar.
20. Clonal Multilineage Differentiation of Murine Common Pluripotent Stem Cells Isolated from Skeletal Muscle and Adipose Stromal Cells: Jamie Case, Tamara L. Horvath, Jonathan C. Howell, Mervin C. Yoder, Keith L. March, and Edward F. Srour.
21. Tracking Hematopoiesis at the Single Cell Level: Timm Schroeder.
22. Lymphoid Potential of Primitive Bone Marrow Progenitors Evaluated In Vitro: Hongfang Wang, L Jeanne Pierce, and Gerald J. Spangrude.
.
Part VIII: Self-Renewal:.
23. Role of Telomerase in Hematopoietic Stem Cells: Peter M. Lansdorp.
24. The Stem Cell Continuum: Peter J. Quesenberry, Gerald A. Colvin, Mehrdad Abedi, Gerri Dooner, Mark Dooner, Jason Aliotta, Patrick Keaney, Luguang Luo, Delia Demers, Abigail Peterson, Bethany Foster, and Deborah Greer.
25. Human Adaptive Immune System Rag2-/-c-/- Mice: Laurie Chicha, Roxane Tussiwand, Elisabetta Traggiai, Luca Mazzucchelli, Lucio Bronz, Jean-Claude Piffaretti, Antonio Lanzavecchia, and Markus G. Manz
- Volume
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6: paper ISBN 9781573316767
Description
Stem cell research holds great promise for therapeutic applications. This rapidly advancing field is the focus of the biennial international symposium and workshop whose proceedings are contained within this volume. The major topics covered are stem cell function, including self-renewal, survival, migration, and regulation; the stem cell niche; stem cell fate as lineage commitment takes place; malignant hematopoiesis; hematopoiesis regulators; and embryonic stem cells and plasticity.
As with previous volumes in this unique series of proceedings, it is hoped that further cooperation and collaborative projects will be generated by disseminating these presentations widely.
NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.
ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member
Table of Contents
Introduction: Katja C. Weisel, John E. Dick, Willem E. Fibbe, and Lothar Kanz. Part I: Stem Cell Function:.
1. AMD3100 and CD26 Modulate Mobilization, Engraftment, and Survival of Hematopoietic Stem and Progenitor Cells Mediated by the SDF-1/CXCL12-CXCR4 Axis: Hal E. Broxmeyer, Giao Hangoc, Scott Cooper, Timothy Campbell, Shigeki Ito, and Charlie Mantel.
2. The Stem Cell Continuum: Cell Cycle, Injury, and Phenotype Lability: Peter J. Quesenberry, Gerald Colvin, Gerri Dooner, Mark Dooner, Jason M. Aliotta, and Kevin Johnson.
3. Inference, Validation, and Dynamic Modeling of Transcription Networks in Multipotent Hematopoietic Cells: Shamit Soneji, Sui Huang, Matthew Loose, Ian John Donaldson, Roger Patient, Berthold Gottgens, Tariq Enver, and Gillian May.
Part II: Stem Cell Niche:.
4. Maintenance of Quiescent Hematopoietic Stem Cells in the Osteoblastic Niche: Fumio Arai and Toshio Suda.
5. Cytokine Signaling, Lipid Raft Clustering, and HSC Hibernation: Satoshi Yamazaki, Atsushi Iwama, Yohei Morita, Koji Eto, Hideo Ema, and Hiromitsu Nakauchi.
6. Dormant and Self-Renewing Hematopoietic Stem Cells and Their Niches: Anne Wilson, Gabriela M. Oser, Maike Jaworski, William E. Blanco-Bose, Elisa Laurenti, Christelle Adolphe, Marieke A. Essers, H. Robson MacDonald, and Andreas Trumpp.
Part III: Stem Cell Fate:.
7. Cartography of Hematopoietic Stem Cell Commitment Dependent upon a Reporter for Transcription Factor Activation: Koichi Akashi.
8. Gradients of Antigen Expression and Developmental Potential in Hematopoiesis: Jae-Yong Kwak, Scott Cho, and Gerald J. Spangrude.
9. Biological and Molecular Evidence for Existence of Lymphoid-Primed Multipotent Progenitors: Sidinh Luc, Natalija Buza-Vidas, and Sten Eirik W. Jacobsen.
Part IV: Malignant Hematopoiesis:.
10. Insertional Mutagenesis by Replication-Deficient Retroviral Vectors Encoding the Large T Oncogene: Zhixiong Li, Olga S. Kustikova, Kenji Kamino, Thomas Neumann, Mathias Rhein, Elke Grassman, Boris Fehse, and Christopher Baum.
11. NUP98 Dysregulation in Myeloid Leukemogenesis: M. A. S. Moore, K. Y. Chung, M. Plasilova, J. J. Schuringa, J.-H. Shieh, P. Zhou, and G. Morrone.
Part V: Regulators:.
12. LEF-1 Is a Decisive Transcription Factor in Neutrophil Granulopoiesis: Julia Skokowa and Karl Welte.
13. Role of Thrombopoietin in Mast Cell Differentiation: Anna Rita Migliaccio, Rosa Alba Rana, Alessandro M. Vannucchi, and Francesco A. Manzoli.
14. Thrombopoietic Cells and the Bone Marrow Vascular Niche: H. G. Kopp and S. Rafii.
15. Differential Effects of G Protein-Coupled Receptors on Hematopoietic Progenitor Cell Growth Depend on their Signaling Capacities: Xingkui Xue, Zhen Cai, Gabriele Seitz, Lothar Kanz, Katja C. Weisel, and Robert Mohle.
16. Effect of FLT3 Inhibition on Normal Hematopoietic Progenitor Cells: Katja C. Weisel, Sedat Yildirim, Eric Schweikle, Lothar Kanz, and Robert Mohle.
Part VI: Embryonic Stem Cells and Plasticity:.
17. The Cdx-Hox Pathway in Hematopoietic Stem Cell Formation from Embryonic Stem Cells: Claudia Lengerke, Shannon Mckinney-Freeman, Olaia Naveiras, Frank Yates, Yuan Wang, Dimple Bansal, and George Q. Daley.
18. Differentiation Potential of Histocompatible Parthenogenetic Embryonic Stem Cells: Claudia Lengerke, Kitai Kim, Paul Lerou, and George Q. Daley.
19. Hematopoiesis from Human Embryonic Stem Cells: Mickie Bhatia.
20. Emergence of Human Angiohematopoietic Cells in Normal Development and from Cultured Embryonic Stem Cells: Elias T. Zambidis, Lidia Sinka, Manuela Tavian, Venta Jokubaitis, Tea Soon Park, Paul Simmons, and Bruno Peault.
Part VII: Stem Cell Exhaustion:.
21. Epigenetic Control of Hematopoietic Stem Cell Aging: The Case of Ezh2: Gerald De Haan and Alice Gerrits.
22. Telomere Length in Human Natural Killer Cell Subsets: Qin Ouyang, Gabriela Baerlocher, Irma Vulto, and Peter M. Lansdorp.
Part VIII: Mesenchymal Stem Cells and Transplantation:.
23. Flt3 in Regulation of Type I Interferon-Producing Cell and Dendritic Cell.
Development: Nobuyuki Onai, Aya Obata-Onai, Michael A. Schmid, and Markus G. Manz.
24. Novel Markers for the Prospective Isolation of Human MSC: Hans-J Org Buhring, Venkata Lokesh Battula, Sabrina Treml, Bernhard Schewe, Lothar Kanz, and Wichard Vogel.
25. Modulation of Immune Responses by Mesenchymal Stem Cells: Willem E. Fibbe, Alma J. Nauta, and Helene Roelofs.
26. Feasibility and Outcome of Reduced-Intensity Conditioning in Haploidentical Transplantation: Rupert Handgretinger, Xiaohua Chen, Matthias Pfeiffer, Ingo Mueller, Tobias Feuchtinger, Gregory A. Hale, and Peter Lang
- Volume
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7: paper ISBN 9781573317610
Description
A fundamental property of hematopoetic stem cells is their capacity to self-renew, thus providing, in principle, a limitless source of daughter cells and with the same functional properties. This volume presents the most recent developments, and their clinical implications, in hematopoietic stem cell research. The field of hematopoietic stem cell biology is rapidly advancing and new ideas and concepts supported by new technologies provide new discoveries. Topics covered are genetic and epigenetic regulation of stem cells, stem cell plasticity, stem cell regulation and self-renewal, and embryonic stem cells as well as malignant stem cell biology. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.
ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Table of Contents
Part I. Stem Cell Hierachy and Niche. 1. Lymphoid lineage fate decision of hematopoietic stem cells (Koichi Akashi).
2. Genetic Models to Study Quiescent Stem Cells and Their Niches (Christoph Schaniel and Kateri A. Moore).
3. Niche regulation of hematopoietic stem cells in the endosteum: the role of Thrombopoietin/Mpl signaling in the maintenance of quiescent hematopoietic stem cells (Fumio Arai, Hiroki Yoshihara, Kentaro Hosokawa, Yuka Nakamura, Yumiko Gomei, Hiroko Iwasaki, and Toshio Suda).
4. Functional Heterogeneity of the Bone Marrow Vascular Niche (K. Hans Georg Kopp, Andrea T. Hooper, Scott T. Avecilla, and Shahin Rafii).
Part II. Stem Cell Regulation.
5. Complex and Context Dependent Regulation of Hematopoiesis by TGF- Superfamily Signaling (Sofie Singbrant Soederberg, Goeran Karlsson, and Stefan Karlsson).
6. WNT Proteins: Environmental factors regulating HSC fate in the niche (Tiago C. Luis and Frank J.T. Staal).
7. Removal of the Spleen in Mice Alters the Cytokine Expression Profile of the Marrow Microenvironmement and Increases Bone Formation (Fabrizio Martelli, Maria Verrucci, Giovanni Migliaccio, Maria Zingariello, Rosa Alba Rana, Alessandro Maria Vannucchi, and Anna Rita Migliaccio).
8. Novel trafficking routes for hematopoietic stem and progenitor cells (Steffen Massberg and Ulrich H. von Andrian).
9. Dysregulation of myeloid-specific transcription factors in congenital neutropenia: rescue by NAMPT/NAD+/SIRT1 (Julia Skokowa and Karl Welte).
Part III. Mesenchymal Stem Cells.
10. Mesenchymal stromal cells: a novel treatment modality for tissue repair (Maria Ester Bernardo, Franco Locatelli, and Willem E. Fibbe).
11. Perivascular Multipotent Progenitor Cells in Human Organs (Mihaela Crisan, Chien-Wen Chen, Mirko Corselli, Gabriella Andriolo, Lorenza Lazzari, and Bruno Peault).
12. Phenotypic characterization of distinct human bone marrow-derived MSC subsets (Hans-Joerg Buhring, Sabrina Treml, Flavianna Cerabona, Peter de Zwart, Lothar Kanz, and Malgorzata Sobiesiak).
13. In vitro myogenic differentiation of human bone marrow-derived mesenchymal stem cells as a potential treatment for urethral sphincter muscle repair (Adriana C. Drost, Sibylle Weng, Gerhard Feil, Jochen Schafer, Simon Baumann, Lothar Kanz, Karl-Dietrich Sievert, Arnulf Stenzl, and Robert Moehle).
Part IV. Malignant Hematopoiesis and Cancer Stem Cells.
14. Transformation from Committed Progenitor To Leukemia Stem Cells (Andrei V. Krivtsov, Zhaohui Feng, and Scott A. Armstrong).
15. The role of PLZF in human myeloid development (John E. Dick and Sergei Doulatov).
16. Anti-Tumor Immunity and Cancer Stem Cells (Tobias Schatton and Markus H. Frank).
17. Natural genetic diversity as a means to uncover stem cell regulatory pathways (Gary Van Zant and Ying Liang).
Part V. Aging.
18. Short Telomeres Resulting from Heritable Mutations in the Telomerase Reverse Transcriptase Gene Predispose for a Variety of Malignancies (Mark Hills and Peter M. Lansdorp).
Part V. Pluripotency.
19. Disease models from pluripotent stem cells: turning back time in disease pathogenesis? (Claudia Lengerke and George Q. Daley).
20. Tumors originating from induced pluripotent stem cells and methods for their prevention (Dirk Duinsbergen, Daniela Salvatori, Malin Eriksson, and Harald Mikkers).
21. Fetal Liver Very Small Embryonic/Epiblast Like Stem Cells (VSELs) Follow Developmental Migratory Pathway of Hematopoietic Stem Cells (Ewa K. Zuba-Surma, Magda Kucia, Liu Rui, Wojtek Wojakowski, Janina Ratajczak, and Mariusz Z. Ratajczak).
22. Hematopoietic Development from Human Induced Pluripotent Stem Cells (Claudia Lengerke, Matthias Grauer, Nina I. Niebuhr, Tamara Riedt, Lothar Kanz, In-Hyun Park, and George Q. Daley).
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