Mast cells in allergic diseases
Author(s)
Bibliographic Information
Mast cells in allergic diseases
(Chemical immunology and allergy / series editors, Johannes Ring, Luciano Adorini, Claudia Berek, v. 87)
Karger, c2005
Available at 11 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Includes bibliographical references and indexes
Description and Table of Contents
Description
The discovery of IgE and its association with mast cell histamine release provided the initial understanding of the role of mast cells in asthma and acute allergic reactions. However, mast cells are now recognized as tissue-dwelling effector cells that play multiple roles not only in immediate-type allergic reaction but also in innate immunity, inflammation, angiogenesis, and tissue remodeling. Mast cells produce a variety of lipid mediators, chemokines, cytokines, and enzymes that may interact with inflammatory tissues such as asthmatic lungs. This book focuses on the roles of mast cell products in allergic diseases and discusses strategies to regulate mast cell functions without perturbing their physiological roles. It also aims at understanding mast cells at the system level by creating a detailed model of cell regulation which is expected to lead to highly mast cell-specific, i.e. efficient and safe, drug targets. Allergologists, immunologists and pharmacologists interested in developing new drugs for allergies will benefit from these timely reviews.
Table of Contents
- Preface: Saito, H
- Regulation of Mast Cell Development: Shiohara, M.
- Koike, K
- Regulation of Mast Cell Activation through Fc[epsilon]RI: Yamasaki, S.
- Saito, T
- Role of Oxidants in Mast Cell Activation: Suzuki, Y.
- Yoshimaru, T.
- Inoue, T.
- Niide, O.
- Ra, C
- Roles of Adaptor Molecules in Mast Cell Activation: Tkaczyk, C.
- Iwaki, S.
- Metcalfe, D.D.
- Gilfillan, A.M
- Eicosanoid Mediators of Mast Cells: Receptors, Regulation of Synthesis, and Pathobiologic Implications: Boyce, J.A
- Role of Mast Cell Proteases in Tissue Remodeling: Saito, H
- Mast Cell Mediators in Airway Remodeling: Oh, C.K
- Mast Cell-Derived Cytokine Expression Induced via Fc Receptors and Toll-Like Receptors: Okayama, Y
- Mast Cells in Allergic Airway Disease and Chronic Rhinosinusitis: Pawankar, R
- Chemokine Receptor Expression by Mast Cells: Juremalm, M.
- Nilsson, G
- Mast Cell [beta]2-Adrenoceptors: Kay, L.J.
- Peachell, P.T
- Potential Role of Stem Cell Factor in the Asthma Control by Glucocorticoids: Da Silva, C.A.
- Frossard, N
- Mast Cell Ion Channels: Bradding, P
- Using Mast Cell Knock-In Mice to Analyze the Roles of Mast Cells in Allergic Responses in vivo: Tsai, M
- Grimbaldeston, M.A.
- Yu, M.
- Tam, S.-Y.
- Galli, S.J
- Mast Cell-Specific Genes - New Drug Targets/Pathogenesis: Saito, H.
by "Nielsen BookData"