IGF-I and IGF binding proteins : basic research and clinical management

Author(s)

    • Cianfarani, Stefano
    • Clemmons, David R.
    • Savage, Martin O.

Bibliographic Information

IGF-I and IGF binding proteins : basic research and clinical management

volume editors, Stefano Cianfarani, David R. Clemmons, Martin O. Savage

(Endocrine development / editor, M. O. Savage, v. 9)

Karger, c2005

Available at  / 2 libraries

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Note

Includes bibliographical references and index

ISSN:1421-7082

Description and Table of Contents

Description

The IGF system pervades the fields of development, linear and cellular growth and metabolism. Not only is the functional integrity of the IGF system crucial for normal linear growth and metabolism, it is also of fundamental importance for normal fetal development. This book consists of a compilation of chapters based on presentations at a symposium entitled 'IGFs and IGFBPs: Assessment and Therapeutic Benefit'. Highly qualified basic scientists and endocrinologists report new advances in the broad field of IGF physiology and pathophysiology, related to clinical medicine. New and topical areas of the IGF field are covered, focussing particularly on clinically relevant topics related to growth, pediatric and adult growth hormone deficiency, metabolic disorders, diabetes mellitus and neurology. Molecular and developmental defects are discussed, as are the contributions to clinical diagnosis and management of measurement of IGFs and IGFBPs. The therapeutic potential of recombinant human IGFs and IGFBPs in a range of disorders is also covered. The present volume of Endocrine Development will be of particular interest to scientists and clinicians working in IGF and IGF-related fields and to clinicians working in both pediatric and adult endocrinology and metabolism.

Table of Contents

  • Foreword: Savage, M.O.
  • Preface: Cianfarani, S.
  • Clemmons, D.R.
  • Savage, M.O.
  • Basic Research
  • The IGF System: New Developments Relevant to Pediatric Practice: Rosenfeld, R.G.
  • Clinical Relevance of Systemic and Local IGF-I: Yakar, S.
  • Pennisi, P.
  • Wu, Y.
  • Zhao, H.
  • LeRoith, D.
  • Cartilage Disorders: Potential Therapeutic Use of Mesenchymal Stem Cells: Spagnoli, A.
  • Longobardi, L.
  • O'Rear, L.
  • Treatment in Animal Models: Guan, J.
  • Bennet, L.
  • Gluckman, P.D.
  • Gunn, A.J.
  • Insulin-Like Growth Factor-I and Risk of Type 2 Diabetes and Coronary Heart Disease: Molecular Epidemiology: Sandhu, M.S.
  • Clinical Management
  • Quantitative Measurement of IGF-I and Its Use in Diagnosing and Monitoring Treatment of Disorders of Growth Hormone Secretion: Clemmons, D.R.
  • IGF-I and IGFBP-3 Assessment in the Management of Childhood Onset Growth Hormone Deficiency: Cianfarani, S.
  • Liguori, A.
  • Germani, D.
  • IGFs and IGFBPs in Adult Growth Hormone Deficiency: Aimaretti, G.
  • Baldelli, R.
  • Cornell, G.
  • Croce, C.
  • Rovere, S.
  • Baffoni, C.
  • Bellone, S.
  • Gasco, V.
  • Granata, R.
  • Grottoli, S.
  • Ghigo, E.
  • Monitoring of Insulin-Like Growth Factors during Growth Hormone Treatment: Adulthood Growth Hormone Deficiency: Monson, J.P.
  • IGFs and IGFBPs in GH Insensitivity: Savage, M.O.
  • Blair, J.C.
  • Jorge, A.J.
  • Street, M.E.
  • Ranke, M.B.
  • Camacho-Hubner, C.
  • Childhood and Adolescent Diabetes: Dunger, D.B.
  • Regan, F.M.
  • Acerini, C.L.
  • Insulin Resistance and Type 2 Diabetes mellitus: Is There a Therapeutic Role for IGF-1?: Moses, A.C.
  • Insulin-Like Growth Factors in the Treatment of Neurological Disease: Leinninger, G.M.
  • Feldman, E.L.
  • Insulin-Like Growth Factor System in Amyotrophic Lateral Sclerosis: Wilozak, N.
  • de Keyser, J.
  • Author Index
  • Subject Index.

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