Diabetes and cardiovascular disease

著者

    • Johnstone, Michael T.
    • Veves, Aristidis

書誌事項

Diabetes and cardiovascular disease

edited by Michael T. Johnstone and Aristidis Veves

（Contemporary cardiology）

Humana Press, c2005

2nd ed

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注記

Includes bibliographical references and index

HTTP:URL=http://www.loc.gov/catdir/toc/ecip056/2005000629.html Information=Table of contents

内容説明・目次

内容説明

The cause of diabetes mellitus is metabolic in origin. However, its major clinical manifestations, which result in most of the morbidity and mortality, are a result of its vascular pathology. In fact, the American Heart Association has recently stated that, "from the point of view of cardiovascular medicine, it may be appropriate to say, diabetes is a cardiovascular disease" (1). But diabetic vascular disease is not limited to just the macrovasculature. Diabetes mellitus also affects the microcirculation with devastating results, including nephropathy, neuropathy, and retinopathy. Diabetic nephropathy is the leading cause of end-stage renal disease in the United States, while diabetic retinopathy is the leading cause of new-onset blindness in working-age Americans. The importance of this text on Diabetes and Cardiovascular Disease is evident by the magnitude of the population affected by diabetes mellitus. Over 10 million Americans have been diagnosed with diabetes mellitus, while another 5 million remain undiagnosed. The impact from a public health perspective is huge and increasing. As the population of the United States grows older, more sedentary, and obese, the risk of developing diabetes and its complications will increase. Epidemiological studies have identified diabetes mellitus as a major independent risk factor for cardiovascular disease. Over 65% of patients with diabetes mellitus die from a cardiovascular cause. The prognosis of patients with diabetes mellitus who develop overt clinical cardiovascular disease is much worse than those cardiovascular patients free of diabetes mellitus.

目次

Part I. Pathophysiology Effects of Insulin on the Vascular System Helmut O. Steinberg Effects of Diabetes and Insulin Resistance on Endothelial Functions Zhiheng He, Keiko Naruse, and George L. King Diabetes and Advanced Glycoxidation End-Products Melpomeni Peppa, Jaime Uribarri, and Helen Vlassara The Renin-Angiotensin System in Diabetic Cardiovascular Complications Edward P. Feener PPARs and Their Emerging Role in Vascular Biology, Inflammation, and Atherosclerosis Jorge Plutzky Diabetes and Thrombosis David J. Schneider and Burton E. Sobel Role of Estrogens in Vascular Disease in Diabetes: Lessons Learned From the Polycystic Ovary Syndrome Agathocles Tsatsoulis and Panayiotis Economides Poly(ADP-Ribose) Polymerase Activation and Nitrosative Stress in the Development of Cardiovascular Disease in Diabetes Pal Pacher and Csaba Szabo Adiponectin and the Cardiovascular System Suketu Shah, Alina Gavrila, and Christos S. Mantzoros Nitric Oxide and Its Role in Diabetes Mellitus Michael T. Johnstone and Eli Gelfand Diabetes and Atherosclerosis Maria F. Lopes-Virella and Gabriel Virella The Use of Animal Models to Study Diabetes and Atherosclerosis and Potential Anti-Atherosclerotic Therapies Peter D. Reaven and Wulf Palinski Part II. Clinical A. Risk Factors The Metabolic Syndrome and Vascular Disease S. J. Creely, Aresh J. Anwar, and Sudhesh Kumar Diabetes and Hypertension Samy I. McFarlane, Amal F. Farag, David Gardner, and James R. Sowers Diabetes and Dyslipidemia Asha Thomas-Geevarghese, Catherine Tuck, and Henry N. Ginsberg B. Microcirculation Diabetic Retinopathy Lloyd Paul Aiello and Jerry Cavallerano Diabetic Nephropathy Richard J. Solomon and BijanRoshan Diabetic Neuropathy Rayaz A. Malik and Aristidis Veves Microcirculation of the Diabetic Foot Chantel Hile and Aristidis Veves C. Cardiovascular System: Peripheral Vascular System Epidemiology of Peripheral Vascular Disease Stephanie G. Wheeler, Nicholas L. Smith, and Edward J. Boyko Noninvasive Methods to Assess Vascular Function and Pathophysiology Peter G. Danias and Rola Saouaf Peripheral Vascular Disease in Patients With Diabetes Mellitus Bernadette Aulivola, Allen D. Hamdan, and Frank W. LoGerfo Therapeutic Interventions to Improve Endothelial Function in Diabetes Lalita Khaodhiar and Aristidis Veves D. Cardiovascular System: Cardiac Preoperative Assessment and Perioperative Management of the Surgical Patient With Diabetes Mellitus Alanna Coolong and Mylan C. Cohen Diabetes and Percutaneous Interventional Therapy David P. Lorenz, Joseph P. Carrozza, and Lawrence Garcia Cardiac Surgery and Diabetes Mellitus Tanveer A. Khan, Pierre Voisine, and Frank W. Sellke Heart Failure and Cardiac Dysfunction in Diabetes Lawrence H. Young, Raymond R. Russell, III, and Deborah Chyun Diabetes Mellitus and Heart Disease Michael T. Johnstone and George P. Kinzfogl Index

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