Toxicology of the pancreas
著者
書誌事項
Toxicology of the pancreas
(Target organ toxicology series)
Taylor & Francis, 2006
大学図書館所蔵 全5件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
The increased incidence of pancreatic cancer in the Western world and its grave prognosis has resulted in an urgency for research in this area. Until now the available data on toxicology of the pancreas has been few and fragmentary, scattered throughout the literature. A benchmark volume, Toxicology of the Pancreas pulls together information in this neglected area of toxicological research and highlights fundamental research performed in the last ten years.
Leaders in the field discuss important structures, the detoxification and toxification process at the cellular and sub-cellular level, the distribution of phase 1 and phase 2 drug-metabolizing enzymes and their role in pancreatic disease, and the role of diet and toxicants on pancreatic disease. The book also covers the role of altered genes in the integrity of the pancreas and explores comparative toxicology in humans and in the lab species used in testing.
Illustrated with histological, electron microscopical, and immunohistochemical formats, this book provides a comprehensive and novel presentation of biological and toxicological data. It stands alone as a reliable resource of information easily accessible to professionals in different disciplines.
目次
Developmental Biology of the Vertebrate Pancreas. Gross Anatomy of the Pancreas. Fine Structure of the Pancreas, Vascular Anatomy of the Pancreas. Centroacinar Cells - A Neglected Essential Element of the Pancreas. Physiology of Exocrine Pancreas. Drug-Metabolizing Enzymes in the Human Pancreas. Drug-Metabolizing Enzymes in the Pancreas of Animals. Pancreatic Exocrine-Endocrine Interaction. Nutritional Requirements of the Pancreas. Activity of Pancreatic Secretory Trypsin Inhibitor Is Essential against Pancreatotoxic Factors. Pathological Perspectives of Pancreatic Mucins. Growth Factors in Pancreatic Diseases. Toxicology of Natural Hormones and Hormonelike Chemicals. Alcohol and Pancreatitis. Chronic Pancreatitis: the Initial Tissue Damage and the Resulting Fibrosis Patterns. Chemically Induced Exocrine Degeneration, Atrophy, and Arterial Diseases in Rats. Chronic Pancreatic Toxicity - Role of Stem Cells in the Conversion of Pancreas to Liver. Environmental Factors and Exocrine Pancreatic Disease. Environmental Determinants of Exocrine Pancreatic Cancer. The Effects of Nutrients on Pancreatic Malignancy: Part II - Experimental Studies. Toxicity of Tobacco-Specific N-Nitrosamines. Role of Genetic Factors in Inflammatory Diseases of the Pancreas. Genetic Disorders Associated with Exocrine and Endocrine Pancreatic Tumors. Cystic Fibrosis of the Pancreas - the Disease and Its Manifestations. Toxicology of the Endocrine Pancreas. Alterations of the Endocrine Pancreas. Pancreatic Cancer and Diabetes - Cellular Origin of Adeonocarcinoma. Index.
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