Cystic fibrosis in the 21st century

著者

    • Bush, Andrew
    • Eric W.F.W. Alton
    • Davies, Jane C.
    • Griesenbach, Uta
    • Jaffe, Adam

書誌事項

Cystic fibrosis in the 21st century

volume editors, Andrew Bush, Eric W.F.W. Alton, Jane C. Davies, Uta Griesenbach, Adam Jaffe

(Progress in respiratory research, v. 34)

Karger, 2006

タイトル別名

Cystic fibrosis in the twenty-first century

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注記

Includes bibliographical references and indexes

内容説明・目次

内容説明

Cystic fibrosis used to be thought of as a respiratory and digestive disease, with a uniformly and rapidly fatal outcome. The spectrum of the disease has broadened into the mild atypical case, presenting in middle age, with the potential for complications in virtually every system of the body. In the past few years there has been an explosion of knowledge of the basic science of the defect. The editors have therefore invited the leading scientists and clinicians in the field of cystic fibrosis to describe the recent advances in this disease. Although there are many 'Recent Advances' texts, previous books have been selective in their choice of topics. This book is the first to cover the entire field of this complex disease, and encompasses the rapidly moving topics of the basic molecular and cellular biology as well as the recent multi-system, multi-disciplinary advances in the clinical care of patients. The authors have been charged with writing only about new developments and not to rehash old literature. The bulk of the references is therefore less than five years old. This book addresses all professionals who treat cystic fibrosis and want to have an update of new findings in the field, particularly of those outside their immediate specialisation. It will also be useful for basic researchers interested in related scientific areas and the clinical context of their work.

目次

  • Part One: The Basics
  • The CFTR Gene: Structure, Mutations and Specific Therapeutic Approaches: Nissim-Rafinia, M.
  • Linde, L.
  • Kerem, B.
  • Exquisite and Multi-Level Regulation of CFTR Expression: Trezise, A.E.O.
  • Intracellular Processing of CFTR: Barriere, H.
  • Lukacs, G.L.
  • Structure of the Cystic Fibrosis Transmembrane Conductance Regulator: Stratford, F.L.L.
  • Bear, C.E.
  • Function of CFTR Protein: Ion Transport: Chen, J-H
  • Cai, Z.
  • Li, H.
  • Sheppard, D.N.
  • Cystic Fibrosis. Function of CFTR Protein: Regulatory Functions: Coakley, R.D.
  • Stutts, M.J.
  • Function of CFTR Protein: Developmental Role: Gill, D.
  • Larson, J.E.
  • Genotype-Phenotype Correlations in Cystic Fibrosis: Dorfmann, R.
  • Zielenski, J.
  • Diagnosis of Cystic Fibrosis, CFTR-Related Disease and Screening: Karczeski, B.A.
  • Cutting, G.R.
  • CF Modifier Genes: Griesenbach, U.
  • Alton, E.W.F.W.
  • Davies J.C.
  • Animal Models: Dorin, J.R.
  • In vitro/ex vivo Fluorescence Assays of CFTR Chloride Channel Function: Verkman, A.S.
  • Galietta, L.J.V.
  • In vivo Measurement of Airway Potential Difference to Assess CFTR Function in Man: Middleton, P.
  • Alton, E.W.F.W.
  • Arrays and Proteomics: Ogilvie, V.
  • MacGregor, G. Part Two: The Airway
  • Pathogenesis of Pulmonary Disease in Cystic Fibrosis: Mall, M.
  • Boucher, R.C.
  • Infection vs Inflammation: Ziady, A.G.
  • Davis, P.B.
  • Pseudomonas aeruginosa: Clinical Research: Armstrong, D.
  • Pseudomonas aeruginosa: Basic Research: Scott, F.W.
  • Pitt, T.L.
  • Other Gram-Negative Organisms - Burkholderia cepacia Complex and Stenotrophomonas maltophilia: Govan, J.R.W.
  • Staphylococcus aureus and MRSA: Conway, S.
  • Denton, M.
  • Nontuberculous Mycobacterial Lung Disease in Patients with Cystic Fibrosis: Griffith, D.E.
  • Respiratory Fungal Infections and Allergic Bronchopulmonary Aspergillosis: Que, C.
  • Geddes, D.
  • Advanced Disease Management and Advances in Transplant Medicine: Carby, M.R.
  • Hodson, M.E.
  • Current and Novel Antimicrobial Approaches: Davies, J.C.
  • Anti-Inflammatory Agents - A Clinical Perspective: Hilliard, T.N.
  • Balfour-Lynn, I.M.
  • Recent Advances in Infant and Pre-School Lung Function: Ranganathan, S.
  • Recent Advances in Imaging: Oikonomou, A.
  • Hansell, D.M.
  • New Pharmacological Approaches for Treatment of Cystic Fibrosis: Rubenstein, R.C.
  • Gene and Stem Cell Therapy: Boyd, A.C.
  • Part Three: Digestive Tract
  • Gut Disease: Clinical Manifestations, Pathophysiology, Current and New Treatments: Taylor, C.J.
  • Hardcastle, J.
  • Pancreatic Involvement: Clinical Manifestations, Pathophysiology and New Treatments: Lindley, K.J.
  • Cystic Fibrosis: Liver Disease: Westaby, D.
  • Part Four: Other Organs
  • Fertility, Contraception, Incontinence and Pregnancy: Thorpe-Beeston, J.G.
  • Arthritis, Vasculitits and Bone Disease: Elkin, S.
  • Diabetes in Cystic Fibrosis: Bridges, N., Spowart, K.
  • Part Five: Multidisciplinary Care
  • Challenges for Nurses: Madge, S.
  • Dietetics: Wolfe, S.
  • Morton, A.
  • Physiotherapy: Pryor, J.A.
  • Main, E.
  • Agent, P.
  • Bradley, J.M.
  • Psychological Interventions: Bryon, M.
  • Part Six: The Future
  • The Future: Bush, A.
  • Griesenbach, U.
  • Davies, J.C.
  • Alton, E.W.F.W.
  • Jaffe, A.

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