Power, sex, suicide : mitochondria and the meaning of life

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Bibliographic Information

Power, sex, suicide : mitochondria and the meaning of life

Nick Lane

Oxford University Press, c2005

Available at  / 6 libraries

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Note

Includes bibliographical references and index

Contents of Works

  • The deepest evolutionary chasm
  • Quest for a progenitor
  • The hydrogen hypothesis
  • The meaning of respiration
  • Proton power
  • The origin of life
  • Why bacteria are simple
  • Why mitochondria make complexity possible
  • The power laws of biology
  • The warm-blooded revolution
  • Conflict in the body
  • Foundations of the individual
  • The asymmetry of sex
  • What human prehistory says about the sexes
  • Why there are two sexes
  • The mitochondrial theory of ageing
  • Demise of the self-correcting machine
  • A cure for old age?

Description and Table of Contents

Description

Power, Sex, Suicide, Complexity, Individuality, Fertility, Prehistory, Ageing, Death - these universal themes are all linked by mitochondria - the tiny structures located inside our cells - miniature powerhouses that use oxygen to generate power. There are hundreds of them in each cell, some 10 million billion in a human being. Once considered menial slaves, mere workhorses for complex cells with nuclei, their significance is now undergoing a radical revision. Mitochondria are now seen as the key ingredient that made complex life possible at all. For two billion years, bacteria ruled the earth without ever generating true complexity - a stasis that may still grip life on other planets. Then the union of two bacterial cells led to an evolutionary big bang, from which algae, fungi, plants and animals emerged. For mitochondria were once free-living bacteria, and still retain unmistakable traits of their ancestry, including some of their original DNA. Ever since their fateful absorption, the tortuous and unpredictable relationship between the mitochondria and their host cells has forced one evolutionary innovation after another. Without mitochondria, nothing would exist of the world we know and love. Their story is the story of life itself. Today, mitochondria are central to research into human prehistory, genetic diseases, cell suicide, fertility, ageing, bioenergetics, sex and the eukaryotic cell. Piecing together puzzles from the forefront of research, this book paints a sweeping canvas that will thrill all who are interested in biology, while also contributing to evolutionary thinking and debate. This is a book full of startling insights into the nature and evolution of life, and should be read by anyone who wants to know why we're here.

Table of Contents

  • 1. Introduction: Mitochondria - clandestine rulers of the world
  • 2. Hopeful monster - the origin of the eukaryotic cell
  • 3. The vital force: Proton power and the origin of life
  • 4. Insider deal: Why mitochondria are needed for the evolution of complexity
  • 5. Power laws: Size and the ramp of ascending complexity
  • 6. Power, sex, suicide: The troubled birth of the individual
  • 7. Battle of the sexes: Human prehistory and the nature of gender
  • 8. Clock of life: Why mitochondria kill us in the end

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