Antiretroviral therapy

Bibliographic Information

Antiretroviral therapy

edited by Erik D.A. de Clercq

ASM Press, c2001

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Includes bibliographies and index

Description and Table of Contents

Description

Authoritative chapters by American and European investigators review new approaches to therapy based on fundamental discoveries on retrovirus infection and reproduction cycle. The volume also covers new approaches to therapy such as the determination of viral load, resistance problems, and the outlook for future advances in antiretroviral therapy.

Table of Contents

1. Kinetics of Human Immunodeficiency Virus Type 1 Replication and Therapy (Bharat Ramratnam and Martin H. Markowitz) 2. Cellular Receptors as Targets for Anti-Human Immunodeficiency Virus Agents (Dominique Schols and Erik De Clercq) 3. Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (J. Balzarini and Erik De Clercq) 4. Nonnucleoside Reverse Transcriptase Inhibitors (J. Balzarini, R. Esnouf, and Erik De Clercq) 5. Human Immunodeficiency Virus Type 1 Integrase-Targeted Inhibitor Design (Nouri Neamate, Christophe Marchand, Heather E. Winslow, and Yves Pommier) 6. Inhibitors of Transcription and Transactivation and Anti-Human Immunodeficiency Virus Agents (Jonathan Karn) 7. Oligonucleotides as Antiretroviral Agents (A. Kirk Field) 8. Protease Inhibitors as Anti-Human Immunodeficiency Virus Agents (Dale J. Kempf, Akhteruzzaman Molla, and Ann Hsu) 9. Glycoprotein Processing Enzymes as a Target for Human Immunodeficiency Virus Chemotherapy (A. Stanley Tyms) 10. Cellular Factors as Targets for Anti-Human Immunodeficiency Virus Therapy (Masanori Baba) 11. Therapeutic Human Immunodeficiency Virus Vaccines: Concept (Current Status, and Future Directions, John S. Lambert, Robert R. Redfield, and Edmund C. Tramont) 12. Clinical Usefulness of Human Immunodeficiency Virus Drug Resistance Monitoring (Anne-Mieke Vandamme and Erik De Clercq) 13. Emergence of Drug-Resistant Human Immunodeficiency Virus Type 1 (HIV-1) Variants and their Impact on Antiretroviral Therapy of HIV-1 Infection (Mark F. Kavlick and Hiroaki Mitsuya) 14. Combination Antiretroviral Therapy (Cecile Tremblay, Joan C. Kaplan, and Martin S. Hirsch) 15. Drug-Drug Interactions in Human Immunodeficiency Virus Infections (Charles W. Flexner and Stephen C. Piscitelli)

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