Toxicology and ecotoxicology in chemical safety assessment

著者

    • Robinson, Laura
    • Thorn, Ian

書誌事項

Toxicology and ecotoxicology in chemical safety assessment

by Laura Robinson and Ian Thorn

Blackwell Pub , CRC Press, c2005

  • : uk
  • : us

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注記

First published as Handbook of toxiocology and ecotoxicology for the pulp and paper industry in 2001 by Blackwell Science

Includes bibliographies and index

内容説明・目次

巻冊次

: us ISBN 9780849324000

内容説明

The use of chemicals in any workplace in the developed world is governed by stringent health, safety and environmental legislation, and companies spend significant amounts of time and money assessing the risks associated with the handling and use of chemicals. In practice, those risk assessments are generally carried out by a range of competent people, be it the corporate safety manager, the R&D chemist or the manufacturing unit manager. This book will guide those personnel in the understanding, interpretation and application of toxicological and ecotoxicological information, supplied on a material safety data sheet, when planning the safe handling and use of chemicals. This volume is directed at corporate health & safety officers and safety managers; R&D chemists; process chemists and engineers, and manufacturing unit managers & supervisors in the pharmaceutical industry and the bulk, fine and specialty chemicals industries.

目次

TOXICOLOGY Introduction Toxicity Chemical Irritancy and Corrosive Effects Chemical Allergies Genetic Toxicology and Carcinogenicity Reproductive Toxicology The Nervous System Alternative to Animal Testing ECOTOXICOLOGY Introduction Aquatic Toxicity Testing Chemical Persistence and Biodegradability Bioaccumulation CLASSIFICATION AND LABELLING OF CHEMICALS ACCORDING TO THEIR HAZARDOUS NATURE Introduction Europe The Dangerous Substances Directive 67/548/EEC Preparations Canada USA Summary HANDLING CHEMICALS IN THE WORKPLACE Introduction Risk Assessment Chemical Hazards CHEMICAL CONTROL Introductions Chemical Control in Europe Chemical Control in the USA Chemical Control in Australia THE MATERIAL SAFETY DATA SHEET Introduction How to Deal with Toxicological or Ecotoxicological Data Gaps Glossary of Terms Index
巻冊次

: uk ISBN 9781405115599

内容説明

The use of chemicals in the workplace is governed by stringent health, safety and environmental legislation, and companies spend significant amounts of time and money assessing the risks associated with the safe handling and use of chemicals. In practice, a range of information is required when assessing the safe handling of chemicals, much of which is provided by the manufacturer in the material safety data sheet. Toxicology and Ecotoxicology in Chemical Safety Assessment is written for corporate health & safety officers and safety managers, R&D chemists, process chemists and engineers, and manufacturing unit managers & supervisors in all industries where chemicals are used. The information contained in this book will help those personnel understand, interpret and apply the range of information supplied on a material safety data sheet when planning the safe handling and use of chemicals. * Provides detailed practical guidance in using supplier Tox/Ecotox data when assessing the risks associated with the industrial handling and use of chemicals. * Data from different manufacturers is often compiled to different standards, using different methodologies. This book will provide the reader with a detailed framework within which to evaluate the data supplied. * Helps readers to plot a commercially realistic path between over- and under-evaluation of the risks and hazards associated with the industrial handling and use of chemicals.

目次

1. Toxicology. Introduction. Toxicity. Chemical irritancy and corrosive effects. Chemical allergies. Genetic toxicology and carcinogenicity. Reproductive toxicology. The nervous system. Alternatives to animal testing. 2. Ecotoxicology. Introduction. Aquatic toxicity testing. Chemical persistence and biodegradability. Bioaccumulation. 3. Classification and labelling of chemicals according to their hazardous nature. Introduction. Europe. The Dangerous Substances Directive 67/548/EEC. Preparations. Canada. USA. Summary. 4. Handling chemicals in the workplace. Introduction. Risk assessment. Chemical harzards. . 5. Chemical control. Introduction. Chemical control in Europe. Chemical control in the USA. Chemical control in Australia. 6. The Material Safety Data Sheet. Introduction. How to deal with differences in toxicological information

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