Handbook of cancer vaccines

著者

書誌事項

Handbook of cancer vaccines

edited by Michael A. Morse, Timothy M. Clay, H. Kim Lyerly

（Cancer drug discovery and development）

Humana Press, c2004

  • : e-book

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注記

Minimum system requirements: Adobe reader 6.0 or later

HTTP:URL=http://www.loc.gov/catdir/toc/ecip044/2003011110.html Information=Table of contents

Includes bibliographies and index

内容説明・目次

巻冊次

ISBN 9781588292094

内容説明

An authoritative survey of the scientific background for therapeutic cancer vaccines, the challenges to their development, and their current uses in treating cancer. The authors examine the basic issues that effect all vaccines (such as immune adjuvants and prime-boost strategies), describe the methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. They also spell out the clinical results for cancer vaccines now beginning to be used in the treatment of many common cancers.

目次

Part I: Basic Science of Tumor Antigens and Immune Activation Biology of the Cancer Vaccine Immune Response Michael A. Morse, Timothy M. Clay, and H. Kim Lyerly The Rational Design of T-Cell Epitopes With Enhanced Immunogenicity John Fikes Identification of Tumor Antigens Using Subtraction and Microarrays Jiangchun Xu Tumor Antigen Discovery With T Cells Paul F. Robbins Targeting Viral Antigens for the Treatment of Malignancies Gretchen L. Eiben, Diane M. Da Silva, Steven C. Fausch, Amanda M. Krier, I. Caroline Le Poole, Megan E. Papineau, Michael I. Nishimura, and W. Martin Kast Immune Defects in Cancer Dmitry Gabrilovich and Vladimir Pisarev Escape of Tumors From the Immune System: Role of the Transforming Growth Factor-b-Signaling Pathway Gerard C. Blobe Part II: General Vaccine and Immunotherapy Strategies Immune Adjuvants Jory R. Baldridge, Susan Hand Zimmermann, and Sally P. Mossman Heterologous Prime-Boost Vaccination in Tumor Immunotherapy Michael J. Palmowski and Caroline Smith Peptide-Based Vaccines Carmen M. Berger, Keith L. Knutson, Lupe G. Salazar, Kathy Schiffman, and Mary L. Disis Antibody-Inducing Cancer Vaccines Against Cell-Surface Carbohydrate Antigens Govind Ragupathi, John Gathuru, and Philip O. Livingston Anti-Idiotype Vaccines Sunil K. Chatterjee, Malaya Bhattacharya-Chatterjee, and Kenneth A. Foon Pox Viral Vaccines James L. Gulley, Philip M. Arlen, and Jeffrey Schlom Utility of Adenovirus-Based Vectors for Multiple Cancer Vaccine Approaches Zachary Hartman and Andrea Amalfitano Alphaviral-Based Strategies for the Immunotherapy of Cancer Edward L. Nelson and Jonathan Smith DNA Vaccines Michael Bereta and Howard L. Kaufman Whole-Cell Vaccines Timothy M. Clay, Paul J. Mosca, H. Kim Lyerly, and Michael A. Morse Gene-Modified Tumor-Cell Vaccines Leisha A. Emens and Elizabeth M. Jaffee Hapten-Modified Tumor Vaccines David Berd Chaperone Proteins/Heat Shock Proteins As Anticancer Vaccines Michael W. Graner and Emmanuel Katsanis Dendritic Cell Vaccines Madhav V. Dhodapkar Exosomes for Immunotherapy of Cancer Nathalie Chaput, N. E. C. Schartz, Fabrice Andre, and Laurence Zitvogel Immunocytokines for Cancer Immunotherapy Paul M. Sondel and Steven D. Gillies T-Cell Adoptive Immunotherapy Gregory E. Plautz, Peter A. Cohen, David E. Weng, and Suyu Shu Part III: Tumor-Specific Vaccine Development Melanoma Vaccines Jeffrey Weber Allogenic Melanoma Lysate Vaccines Malcolm S. Mitchell Renal Cancer Vaccines Hyung L. Kim, Barbara J. Gitlitz, and Robert A. Figlin Vaccines for Hematological Malignancies Qing Yi Vaccines for the Immunotherapy of Prostate Cancer Boris Minev and Michael L. Salgaller Vaccine Therapy for Breast and Ovarian Cancers Susan E. Smith and Alison T. Stopeck Vaccine Therapy for Gastrointestinal Cancers John L. Marshall Vaccines for Lung Cancer Michael A. Morse, Jennifer Garst, and Eric Toloza Vaccines for Other Tumors Michael A. Morse Part IV: Clinical Trials and Immune Analyses Clinical Trial Designs for Therapeutic Vaccine Studies Richard Simon Analysis of Cellular Immune Responses in Cancer Vaccine Trials Timothy M. Clay, Michael A. Morse, Paul J. Mosca, Amy Hobeika, Donna Niedzwiecki, and H. Kim Lyerly Analysis of Humoral Immune Responses in Vaccine Trials Rajasekharan Somasundaram, Tianqian Zhang, and Dorothee Herlyn Regulatory Issues Affecting Tumor Vaccines Mark O. Thornton, Alexand
巻冊次

: e-book ISBN 9781592596805

内容説明

An authoritative survey of the scientific background for therapeutic cancer vaccines, the challenges to their development, and their current uses in treating cancer. The authors examine the basic issues that effect all vaccines (such as immune adjuvants and prime-boost strategies), describe the methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. They also spell out the clinical results for cancer vaccines now beginning to be used in the treatment of many common cancers.

目次

  • Part I: Basic Science of Tumor Antigens and Immune Activation
  • Biology of the Cancer Vaccine Immune Response Michael A. Morse, Timothy M. Clay, and H. Kim Lyerly
  • The Rational Design of T-Cell Epitopes With Enhanced Immunogenicity John Fikes
  • Identification of Tumor Antigens Using Subtraction and Microarrays Jiangchun Xu
  • Tumor Antigen Discovery With T Cells Paul F. Robbins
  • Targeting Viral Antigens for the Treatment of Malignancies Gretchen L. Eiben, Diane M. Da Silva, Steven C. Fausch, Amanda M. Krier, I. Caroline Le Poole, Megan E. Papineau, Michael I. Nishimura, and W. Martin Kast
  • Immune Defects in Cancer Dmitry Gabrilovich and Vladimir Pisarev
  • Escape of Tumors From the Immune System: Role of the Transforming Growth Factor-[beta]-Signaling Pathway Gerard C. Blobe
  • Part II: General Vaccine and Immunotherapy Strategies
  • Immune Adjuvants Jory R. Baldridge, Susan Hand Zimmermann, and Sally P. Mossman
  • Heterologous Prime-Boost Vaccination in Tumor Immunotherapy Michael J. Palmowski and Caroline Smith
  • Peptide-Based Vaccines Carmen M. Berger, Keith L. Knutson, Lupe G. Salazar, Kathy Schiffman, and Mary L. Disis
  • Antibody-Inducing Cancer Vaccines Against Cell-Surface Carbohydrate Antigens Govind Ragupathi, John Gathuru, and Philip O. Livingston
  • Anti-Idiotype Vaccines Sunil K. Chatterjee, Malaya Bhattacharya-Chatterjee, and Kenneth A. Foon
  • Pox Viral Vaccines James L. Gulley, Philip M. Arlen, and Jeffrey Schlom
  • Utility of Adenovirus-Based Vectors for Multiple Cancer Vaccine Approaches Zachary Hartman and Andrea Amalfitano
  • Alphaviral-Based Strategies for the Immunotherapy of Cancer Edward L. Nelson and Jonathan Smith
  • DNA Vaccines Michael Bereta and Howard L. Kaufman
  • Whole-Cell Vaccines Timothy M. Clay, Paul J. Mosca, H. Kim Lyerly, and Michael A. Morse
  • Gene-Modified Tumor-Cell Vaccines Leisha A. Emens and Elizabeth M. Jaffee
  • Hapten-Modified Tumor Vaccines David Berd
  • Chaperone Proteins/Heat Shock Proteins As Anticancer Vaccines Michael W. Graner and Emmanuel Katsanis
  • Dendritic Cell Vaccines Madhav V. Dhodapkar
  • Exosomes for Immunotherapy of Cancer Nathalie Chaput, N. E. C. Schartz, Fabrice Andre, and Laurence Zitvogel
  • Immunocytokines for Cancer Immunotherapy Paul M. Sondel and Steven D. Gillies
  • T-Cell Adoptive Immunotherapy Gregory E. Plautz, Peter A. Cohen, David E. Weng, and Suyu Shu
  • Part III: Tumor-Specific Vaccine Development
  • Melanoma Vaccines Jeffrey Weber
  • Allogenic Melanoma Lysate Vaccines Malcolm S. Mitchell
  • Renal Cancer Vaccines Hyung L. Kim, Barbara J. Gitlitz, and Robert A. Figlin
  • Vaccines for Hematological Malignancies Qing Yi
  • Vaccines for the Immunotherapy of Prostate Cancer Boris Minev and Michael L. Salgaller
  • Vaccine Therapy for Breast and Ovarian Cancers Susan E. Smith and Alison T. Stopeck

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