Calcium channel blockers
Author(s)
Bibliographic Information
Calcium channel blockers
（Milestones in drug therapy）
Birkhäuser, c2004
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Note
Includes bibliographies and index
Description and Table of Contents
Description
The main effect of calcium channel blockers is the blockade of calcium entry into cells through voltage operated calcium channels. This volume gives a comprehensive overview of the different classes of CCBs and their various effects. It covers historical development, pharmacology, clinical aspects, and perspectives. All chapters are written by Prof. T. Godfraind, a world leading expert in the field.
Table of Contents
Historical perspective: from early steps on calcium research to the identification of calcium antagonist prototypes and of the signaling functions of Ca2+.- Calcium channel blockers and calcium channels.- The action of calcium antagonists on Ca2+ movements in isolated vessels.- The tissue selectivity of calcium antagonists.- Acute haemodynamic effects of calcium channel blockers.- Calcium channels and regulation of vascular tone in hypertension.- Long-term effects of calcium antagonists.- Blood pressure-independent effects of calcium antagonists.- From early clinical studies to randomized controlled clinical trials.- Beyond the cardiovascular system.
by "Nielsen BookData"
