Köhler's invention

著者

    • Eichmann, Klaus, b. 1939

書誌事項

Köhler's invention

Klaus Eichmann

Birkhäuser, c2005

大学図書館所蔵 件 / 全2件

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注記

Bibliography: p.[219]-223

内容説明・目次

内容説明

Georges Koehler was one of the most prominent German scientists of recent history. In 1984, at an age of 38, he received the Nobel Prize in Physiology or Medicine, together with N.K. Jerne and C. Milstein, for inventing the technique for generating monoclonal antibodies. This method and its subsequent applications had an enormous impact on basic research, medicine and the biotech industry. In the same year, Koehler became one of the directors of the Max-Planck-Institute of Immunobiology in Freiburg; his unfortunate premature death in 1995 set an end to his extraordinary career. Prof. Klaus Eichmann, who had invited Koehler to become his codirector, is one of the people who were closest to him. This scientific biography commemorates the 10th anniversary of Koehler's untimely death. Koehler's scientific achievements are explained in a way to make them understandable for the general public and discussed in the historical context of immunological research.

目次

The time before.- A short history of the antibody problem.- The immunological scene around Koehler.- Koehler's entry into science.- The quest for monoclonal antibodies.- Cell fusion.- Koehler in Cambridge.- Back in Basel.- The patent disaster.- The time after.- The Max-Planck-Institute of Immunobiology.- Getting Koehler to Freiburg.- "Koehler's Max-Planck-Institute".- Human relations.- Post-Nobel science I.- Post-Nobel science II.- Koehler's death.- Magic bullet.- The antibody problem today - not quite solved.

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