Cancer chemotherapy and biotherapy : principles and practice

Bibliographic Information

Cancer chemotherapy and biotherapy : principles and practice

editors, Bruce A. Chabner, Dan L. Longo

Lippincott Williams & Wilkins, c2006

4th ed

Other Title

Cancer chemotherapy & biotherapy : principles and practice

Available at  / 11 libraries

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Includes bibliographies and index

Description and Table of Contents

Description

Updated to include the newest drugs and those currently in development, this Fourth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition provides expanded coverage of monoclonal antibodies, molecularly targeted drugs, vaccines, cell based therapies, growth factors, and pharmacogenetics.

Table of Contents

<ol> Clinical Strategies Bruce Chabner Preclinical aspects of Cancer Drug Discovery Ed Sausville, Paula Krosky, Melinda Hollingshead, Robert Shoemaker Pharmacokinetics Jerry Collins Infertility Angela Bradbury, Richard Schilsky Carcinogenesis Larry Blaszkowsky Antifolates Carmen Allegra, Brian Monahan Five Fluoropyrimidine Jean Grem Cytidine Analogues David Ryan Purine Analogues Kenneth Hande Hydroxyurea Bruce Chabner Antimicrotuble Agents Eric Rowinsky Alkylating Agents / Clinical & High Dose Roy Jones, Ken Tew Nonclassical Agents Henry Friedman Platinum Analogues Ed Reed Bleomycin Bruce Chabner Antibiotics Kees Nooter, Jaap Verweij, Edwin Willems Topo I: Inhibitors Alex Sparreboom, William Zamboni Topo II: Anthracyclines Jim Doroshow Topo II: Epipodophylotoxins Yves Pommier, Francios Goldwasser L-Asparaginase Bruce Chabner Pharmacology of CNS Agents Jeff Supko FDA Approval Thomas Roberts Catheter and Complications David Kuter, Rachel Rosovsky Pharmacogenetics Robert Diasio, Jeanne Fourie New Agents Louise Grochow Bisphosphonates Matthew Smith Thalidomide Paul Richardson Inhibitors of Tumor Angiogenesis William Gradishar, Anaadriana Zakarija Proteosome Inhibitors Owen O'Connor Molecular Targeted Drugs - Growth Factor Receptor Inhibitors Jeff Clark Monoclonal Antibody Therapies David Scheinberg Interferon Danield Linder, Earnest Borden Adoptive Therapies Carl June Vaccines Glenn Dranoff Hematopoietic Growth Factors William Petros Interleukins Gheath Alatrash, Ronald Bukowski, James Finke, Charles Tannenbaum Hormonal Therapy for Breast Cancer and Prostate Peter Lebowitz, Sandra Swain, Steven Balk

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