GABA in autism and related disorders

Author(s)

• Dhossche, Dirk M.

Bibliographic Information

GABA in autism and related disorders

edited by Dirk M. Dhossche

（International review of neurobiology, v. 71）

Elsevier Academic Press, c2005

Note

Includes bibliographical references and index

Description and Table of Contents

Description

Gamma-aminobutyric acid (GABA) was discovered in the brain in 1950 by Eugene Roberts. GABA is now considered one of the most important neurotransmitters and developmental signals. Knowledge on the complexity of GABA function is increasing exponentially. This volume covers basic research on GABA in the developing brain as it may relate to onset of autism and related developmental disorders. The evidence that dysfunction of GABA and related molecules is associated with autism is limited but expanding and seems to converge. Pertinent data are reviewed in this book and new research avenues in the basic and clinical arenas are described. The topics are of imminent interest to basic and clinical researchers as well as interested clinicians.

Table of Contents

Foreword by Eugene Roberts Autism: neuropathology, alterations of the GABAergic system, and animal models The role of GABA in the early neuronal development GABAergic signaling in the developing cerebellum Insights into GABA functions in the developing cerebellum Role of GABA in the Mechanism of the Onset of Puberty in Non-Human Primates Rett Syndrome: A Rosetta Stone for Understanding the Molecular Pathogenesis of Autism GABAergic Cerebellar System in Autism: A Neuropathological and Developmental Perspective Reelin Glycoprotein in Autism and Schizophrenia Is there a connection between autism, Prader-Willi syndrome, catatonia and GABA? The role of GABA in prenatal alcohol exposure Effects of secretin on extracellular GABA and other amino acid concentractions in the rat hippocampus Predicted therapeutic role of secretin and oxytocin in augism: Implications for treatment of mental illness Immunological Findings in Autism Correlates of psychomotor symptoms in autism Gabrb3 Gene Deficient Mice: A Potential Model of Autism Spectrum Disorder The Reeler Mouse: Anatomy of a Mutant GABA-A receptor mutations in epilepsy and other disorders Shared chromosomal susceptibility regions between autism and other mental disorders

by "Nielsen BookData"

Details

• NCID: BA7510840X
• ISBN:
  • 0123668727
• Country Code: ne
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: Amsterdam
• Pages/Volumes: xxiv, 481 p., [8] p. of col. plates
• Size: 24 cm
• Parent Bibliography ID:
  • BA03981455