Immunopotentiators in modern vaccines
著者
書誌事項
Immunopotentiators in modern vaccines
Elsevier Academic Press, c2006
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations.
目次
Preface
List of contributors
Part I: Perspective on immunological mechanisms underlying adjuvant activity
Chapter 1: Unraveling aEUROoethe immunologist's dirty little secretaEURO
Part II: Host-derived immunopotentiators
Chapter 2: Dendritic cells as targets and tools in vaccines
Chapter 3: Host-derived molecules as adjuvants
Part III: Natural and synthetic immunopotentiators
Chapter 4: Innate immune mechanisms and the identification of immune potentiators as vaccine adjuvants
Chapter 5: CpG oligodeoxynucleotides as vaccine adjuvants
Chapter 6: Toll-like receptor 4 agonists as vaccine adjuvants
Chapter 7: Immunomodulatory adjuvants from Quillaja saponaria
Part IV: Particulate immunopotentiators and delivery systems
Chapter 8: Microparticles as vaccine delivery systems
Chapter 9: MF59: a safe and potent adjuvant for human use
Chapter 10: Development and evaluation of AS04, a novel and improved adjuvant system containing MPL and aluminum salt
Chapter 11: Virosomes for vaccine delivery
Chapter 12: The ISCOMATRIXa"c adjuvant
Chapter 13: Mineral adjuvants
Part V: Mucosal/nonparenteral adjuvants
Chapter 14: Mucosal adjuvants based on cholera toxin and E. coli heat-labile enterotoxin
Chapter 15: Transcutaneous immunization using the heat-labile enterotoxin of E. coli as an adjuvant
Part VI: Th-1/CTL adjuvants
Chapter 16: T cell adjuvants and novel strategies for their identification
Part VII: Adjuvants in noninfectious disease vaccines
Chapter 17: Vaccination to treat noninfectious diseases: surveying the opportunities
Part VIII: Clinical practice
Chapter 18: Clinical evaluation of adjuvants
Chapter 19: Regulatory considerations in the nonclinical safety assessment of adjuvanted preventive vaccines
Index
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