Modeling in biopharmaceutics, pharmacokinetics, and pharmacodynamics : homogeneous and heterogeneous approaches
著者
書誌事項
Modeling in biopharmaceutics, pharmacokinetics, and pharmacodynamics : homogeneous and heterogeneous approaches
（Interdisciplinary applied mathematics, v. 30）
Springer, c2006
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注記
Includes bibliographical references (p.383-432) and index
内容説明・目次
内容説明
This book presents a novel modeling approach to biopharamceutics, pharmacokinetics and pharmacodynamic phenomena. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. Throughout, many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods.
目次
Basic Concepts.- The Geometry of Nature.- Diffusion and Kinetics.- Nonlinear Dynamics.- Modeling in Biopharmaceutics.- Drug Release.- Drug Dissolution.- Oral Drug Absorption.- Modeling in Pharmacokinetics.- Empirical Models.- Deterministic Compartmental Models.- Stochastic Compartmental Models.- Modeling in Pharmacodynamics.- Classical Pharmacodynamics.- Nonclassical Pharmacodynamics.
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