Molecular diagnostics : for the clinical laboratorian
著者
書誌事項
Molecular diagnostics : for the clinical laboratorian
Totowa, N. J., c2006
2nd ed
大学図書館所蔵 件 / 全5件
-
該当する所蔵館はありません
- すべての絞り込み条件を解除する
注記
Includes bibliographical references and index
HTTP:URL=http://www.loc.gov/catdir/toc/ecip052/2004023555.html Information=Table of contents
内容説明・目次
内容説明
In 1994 I coedited a book, Molecular Pathology: Ap- efforts. It should be evident that molecular pathology and proaches to Diagnosing Human Disease in the Clinical diagnostics impact almost every conceivable subspecialty Laboratory, that coined the phrase "molecular pathology" in laboratory medicine and, particularly in the case of to refer to applications of molecular biology in the tradi- pharmacogenomics, have led to the development of new tional areas of laboratory medicine. That compilation of areas of investigation. clinical molecular techniques included 11 chapters and an What is less evident is the burden placed upon the epilogue on "New Directions for the Clinical Laboratory. " laboratorians directing these efforts. Issues regarding Chapter headings included: automation, neoplasia, heri- training, certification, continuing education, and re- table diseases, and infectious diseases. bursement (just to name a few) have demanded enormous Three years later, in 1997, Bill Coleman and Greg Tson- time and effort from professional organizations and g- galis edited Molecular Diagnostics: For the Clinical ernmental agencies.
In addition, because conventional Laboratorian, which contained 18 chapters and introduced approaches cannot always be applied to molecular di- the new areas of RT-PCR and In Situ PCR, and included nostics, unique solutions for quality assurance and quality a section on gene therapy. Now, ten years after the intro- control must be developed. These challenges have eng- duction of molecular pathology, we are looking at the dered committees, subcommittees, taskforces, and second edition of Bill Coleman and Greg Tsongalis' text.
目次
Part I. Introduction
An Historical Perspective on the Clinical Diagnostic Laboratory
Robert E. Moore
Part II. Basic Molecular Biology
An Overview of Nucleic Acid Chemistry, Structure, and Function: The Foundations of Molecular Biology
William B. Coleman
Extraction of Nucleic Acids
Paul N. Bogner and Anthony A. Killeen
Nucleic Acid Blotting Techniques: Theory and Practice
Terry Amiss and Sharon Collins Presnell
The Polymerase Chain Reaction
William B. Coleman and Gregory J. Tsongalis
Bioinformatics: Computer-Based Approaches to Genetic Analysis
Sharon L. Ricketts
Part III. Molecular Diagnostic Technologies
PCR-Based Methods for Mutation Detection
Ian M. Frayling, Emma Monk, and Rachel Butler
Alternative Methods for Amplified Nucleic Acid Testing
Deborah A. Payne and Laurie E. Sower
Electrophoretic Methods for Mutation Detection and DNA Sequencing
W. Edward Highsmith, Jr.
Single-Nucleotide Polymorphisms: Testing DNA Variation for Disease Association
Ulrich Broeckel and Martin J. Hessner
Microarray Approaches to Gene Expression Analysis
David Neil Hayes and Matthew Meyerson
Methods for Analysis of DNA Methylation
Alexander Dobrovic
Part IV. Other Clinical Diagnostic Technologies
Flow Cytometry
Joseph A. DiGiuseppe
Medical Cytogenetics
Martha B. Keagle
Fluorescence In Situ Hybridization: A Major Milestone in Luminous Cytogenetics
Suneel D. Mundle and Robert J. Koska
Immunohistochemistry
John Hunt, Larissa Davydova, Richard W. Cartun, and Maria Baiulescu
Laser Capture Microdissection
C. Robert Bagnell, Jr.
Part V. Quality Assurance in the Molecular Diagnostics Laboratory
Framework for Quality Assurance in Molecular Diagnostics
Marlene Sabbath-Solitare, Selwyn J. Baptist, and Teresita Cuyegkeng Redondo
Verification of Molecular Assays
Brent L. Seaton
Standards and Standardization of Molecular Diagnostics
John P. Jakupciak and Catherine D. O'Connell
Laboratory-Developed Tests in Molecular Diagnostics
Andrea Ferreira-Gonzalez and Carleton T. Garrett
Part VI. Applications of Molecular Diagnostics for Genetic Diseases
An Overview of Molecular Genetics
Elaine Weidenhammer and Gregory J. Tsongalis
Genetic Basis of Neurologic and Neuromuscular Diseases
Narasimhan Nagan, Christopher J. Klein, D. Brian Dawson, Myra J. Wick, and Stephen N. Thibodeau
Molecular Mechanisms of Endocrine Disorders
Amy Potter and John A. Phillips III
Molecular Pathogenesis of Cardiovascular Disease
Alan H. B. Wu
Molecular Diagnostics in Coagulation
Enrique Ballesteros
Cystic Fibrosis
Eugene H. Lewis III, Myra J. Lewis, Jean A. Amos, and Gregory J. Tsongalis
Prenatal Genotyping for Identification of Fetuses at Risk for Immune Cytopenic Disorders
Martin J. Hessner and Brian R. Curtis
Personalized Medicine, Karen McCullough
Part VII. Applications of Molecular Diagnostics for Human Cancers
Molecular Pathogenesis of Human Cancer
William B. Coleman and Gregory J. Tsongalis
Application of Molecular Diagnostics to Hereditary Nonpolyposis Colorectal Cancer
Ian M. Frayling, Lisa Happerfield, Christopher Mattocks, Kim Oakhill, and Mark J. Arends
Molecular Genetic Applications to the Diagnosis of Lymphoma
William N. Rezuke, Jr. and Gregory J. Tsongalis
Molecular Genetic Abnormalities in Acute and Chronic Leukemias
Pei Lin and L. Jeffrey Medeiros
Part VIII. Applications of Molecular Diagnostics for Infectious Diseases
Molecular Testing for Chlamydia trachomatis and Neisseria gonorrhoeae
Alexandra Valsamakis
Human Papillomavirus
Theresa M. Voytek and Gregory J. Tsongalis
「Nielsen BookData」 より