Mitochondria in health and disease
著者
書誌事項
Mitochondria in health and disease
（Oxidative stress and disease / series editors, Lester Packer, Enrique Cadenas, 16）
CRC Press, Taylor & Francis Group, 2005
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注記
Includes bibliographical references and index
収録内容
- Introduction to mitochondria / Carolyn D. Berdanier
- Mitochondrial bioenergetics in intact tissue / Richard L. Veech
- The human mitochondrial genome : mechanisms of expression and maintenance / Jan-Willem Taanman and Siôn Llewellyn Williams
- Oxidative phosphorylation disease : diagnosis and pathogenesis / John M. Shoffner
- Using mitochondrial DNA in population surveys / Carolyn D. Berdanier
- Mitochondrial DNA mutation, oxidative stress, and alteration of gene expression in human aging / Hsin-Chen Lee and Yau-Huei Wei
- Mitochondrial DNA in cardiomyopathies / Nobuakira Takeda
- Mitochondria in Diabetes mellitus / Hong Kyu Lee
- Drugs, nutrients, and hormones in mitochondrial function / Carolyn D. Berdanier
- Bacterial F[1]F[0] ATP synthase as a model for complex V / Brian D. Cain, Tammy Bohannon Grabar, and Deepa Bhatt
- Cybrids in the study of animal mitochondrial genetics and pathology / Ian A. Trounce and Carl A. Pinkert
- Animal modeling : from transgenesis to transmitochondrial models / Carl A. Pinkert and Ian A. Trounce
- BHE/Cdb rats as tools to study mitochondrial gene expression / Carolyn D. Berdanier and Moon-Jeong Chang Kim
内容説明・目次
内容説明
It was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles and their function, it became clear that mitochondrial malfunction could be linked to several chronic diseases. Diabetes has been associated with DNA mutation and can cause mutation itself. This text discusses findings involving the effects of disease on mitochondrial number, mitogenesis, and the base sequence of mitochondrial DNA. Experts discuss their study of mitochondria and what happens when it malfunctions. This book also explores the idea that mutated mitochondrial DNA can result in disease, and vice versa.
目次
Preface. Introduction to Mitochondria. Bioenergetics of Mitochondria. Mitochondrial Genome and Mitochondrial Function. Mitochondrial Diseases in Growth and Development. Using Mitochondria in Population Surveys. Mitochondrial DNA Mutation, Oxidative Stress and Alterations of Gene Expression in Human Aging. Mitochondrial Mutations in Vision. Mitochondrial DNA in Cardiomyopathies. Mitochondria in Diabetes. Drugs, Nutrients and Hormones in Mitochondrial Function. Bacterial F1F0ATP Synthase as a Model for Complex V. Cybrids and the Manipulation of Mitochondrial Genotype. Animal Modeling: From Transgenics to Transmitochondrial Models. BHE/Cdb Rats as Tools to Study Mitochondrial Mutation.
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