Introduction to glycobiology
著者
書誌事項
Introduction to glycobiology
Oxford University Press, c2006
2nd ed
- : pbk
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
We are all familiar with sugar as a vital source of energy. Yet the biological importance of the sugars extends way beyond their value as a cellular fuel. Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their functions at the molecular, cellular, and organismal level. With a new two-part structure, the book leads us through the essential principles and concepts upon which the discipline is grounded, before exploring the diverse roles of sugars throughout biological systems, including development, cell signalling, and protein trafficking. It also describes the importance of glycobiology in disease, and explains how an understanding of the link between the two is enabling us to develop new therapeutic strategies. Taking the student from the fundamental principles to the frontiers of the subject, and with more learning features to get the most from their studies, Introduction to Glycobiology remains the ideal resource for students and teachers alike. Online Resource Centre For Lecturers: - Full Colour figures to fully engage their students during classes.
For Students: - Hyperlinks to the primary literature, and full articles from appropriate OUP journals, to facilitate access to these additional resources - 3D models of key structures, to help students visualize structures, and gain a proper appreciation of the link between structure and function. - Answers to problems, to aid assessment. - Updates - surveys of key developments in the field, provided on a six-monthly basis, to maintain the currency of the resource.
目次
- PART 1: STRUCTURES AND BIOSYNTHESIS OF GLYCANS
- 1. Concepts of glycobiology
- 2. Conformations of oligosaccharides
- 3. N-Linked glycosylation
- 4. O-Linked glycosylation
- 5. Glycolipids and membrane protein glycosylation
- 6. Glycomics: analysis of glycan structures
- PART 2: GLYCANS IN BIOLOGY
- 7. Effects of glycosylation on protein structure and function
- 8. Carbohydrate recognition in cell adhesion and signalling
- 9. Glycoprotein trafficking in cells and organisms
- 10. Glycobiology of plants, bacteria, and viruses
- 11. Glycobiology and development
- 12. Glycosylation and disease
- 13. The future of glycobiology
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