Cell biology of addiction

著者

    • Madras, Bertha

書誌事項

Cell biology of addiction

edited by Bertha Madras ... [et al.]

Cold Spring Harbor Laboratory Press, c2006

大学図書館所蔵 件 / 全4件

この図書・雑誌をさがす

注記

Includes index

内容説明・目次

内容説明

This monograph, written by experts in the field, is devoted to the molecular analysis of addiction pathways in the brain. It provides an intensive overview of the fundamentals, state-of-the-art advances, and major gaps in the cell and molecular biology of drug addiction within the broader context of neuroscience. Addiction research is a branch of neuroscience and psychology. The emphasis in this book is on hard science and the market for it will be found among research investigators and grad students within the field of neuroscience. The research presented is not only applicable to the study of drug abuse and addiction, but has clear implications for clarifying mechanisms of learning and memory, neuroadaptation, perception, volitional behavior, motivation, reward, and other disciplines of neuroscience.

目次

  • 1. Introduction (B.K. Madras) PART 1: GENETICS 2. Addiction Genetics and Genomics (G.R.Uhl) 3. Catechol-O-methyltransferase Genotype, Intermediate Phenotype, and Psychiatric Disorders (K. Xu and D. Goldman) 4. Identifying Genes Affecting Addiction Risk in Animal Models (J.C. Crabbe) 5. Endorphins, Gene Polymorphisms, Stress Responsivity, and Special Addictions: Selected Topics (M.J. Kreek) 6. Imaging the Addicted Brain (N.D. Volkow, G.-J. Wang, J.S. Fowler, and R.Z. Goldstein) 7. Neurotoxin Effects of Drug of Abuse: Imaging and Mechanisms (D.F. Wong) PART 2: DEVELOPMENT AND DRUG ABUSE 8. Development of Midbrain Dopaminergic Pathways (M. Cooper and R. Zhou) PART 3: CELL BIOLOGY AND PHARMACOLOGY 9. Transporter Structure and Function (G. Rudnick) 10. Neuronal Nicotinic Acetylcholine Receptors and Nicotine Dependence (A.R. Tapper, R. Nashmi, and H.A. Lester) 11. Opioids as a Model for Cell Biological Studies of Addictive Drug Action (M. von Zastrow and C.J. Evans) 12. Receptor-receptor Interactions Modulate Opioid Receptor Function (I. Gomes and L.A. Devi) 13. The Endocannabinoid System: From Cell Biology to Therapy (D. Piomelli) 14. Cocaine Neurobiology: From Targets to Treatment (B.K. Madras and Z. Lin) 15. The Oligomerization of G-protein-coupled Receptors (M.M.C. Kong, B.F. O'Dowd, and S.R. George) 16. The Critical Role of Adenosine A2a Receptors and Gi b3
  • Subunits in Alcoholism and Addiction: From Cell Biology to Behavior (I. Diamond and L. Yao) 17. Neurotransmitter Transporters: Mechanisms and Function (R. Edwards) PART 4: SYNAPTIC PLASTICITY AND ADDICTION 18. Synaptic Vesicle Trafficking and Drug Addiction in Synapsin Triple Knockout Mice (D. Gitler, J. Feng, Y. Takagishi, V.M. Pogorelov, R.M. Rodriguiz, B.J. Venton, P.E.M. Phillips, Y. Ren, H.-T. Kao, M. Wightman, P. Greengard, W.C. Wetsel, and G.J. Augustine) 19. Synaptic Plasticity in the Mesolimbic Dopamine System and Addiction (D. Saal and R.C. Malenka) 20. Long-term Memory Storage in Aplysia (J.H. Schwartz) 21. Molecular Mechanisms of Drug Addiction (E.J. Nestler) PART 5: SYSTEMS ANALYSIS OF DRUG ABUSE 22. Dynamic Analyses of Neural Representations Using the State-space Modeling Paradigm (E.N. Brown and R. Barbieri) 23. Quantitative Functional Genomics and Proteomics of Drug Abuse (W.M. Freeman and K.E. Vrana) Index

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