Dipeptidyl aminopeptidases : basic science and clinical applications
著者
書誌事項
Dipeptidyl aminopeptidases : basic science and clinical applications
(Advances in experimental medicine and biology, v. 575)
Springer, c2006
大学図書館所蔵 全8件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
This is the first comprehensive volume on Dipeptidyl Aminopeptidases that can be marketed to a wide variety of disciplines, as well as to a variety of clinicians. Leading experts in the field contribute to this state-of-the-art view on these enzymes. This book comes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent.
目次
Structure and Function.- Peptide Substrates of Dipeptidyl Peptidases.- Phosphorus-Containing Inhibitors of Proteolytic Enzymes.- Biochemical Properties of Recombinant Prolyl Dipeptidases DPP-IV and DPP8.- Prediction of Dipeptidyl Peptidase (DP) 8 Structure by Homology Modelling.- Dpiv-Related Enzymes.- Structure and Function in Dipeptidyl Peptidase IV and Related Proteins.- Expression and Function of Dipeptidyl Peptidase IV and Related Enzymes in Cancer.- DP8 and DP9 have Extra-Enzymatic Roles in Cell Adhesion, Migration and Apoptosis.- In Vivo Effects of a Potent, Selective Dppii Inhibitor.- Expression of Dipeptidyl Peptidase IV-Like Enzymes in Human Peripheral Blood Mononuclear Cells.- Dipeptidyl Peptidase 8 Has Post-Proline Dipeptidyl Aminopeptidase and Prolyl Endopeptidase Activities.- Prolyl Endopeptidase Cleaves the Apoptosis Rescue Peptide Humanin and Exhibits an Unknown Post-Cysteine Cleavage Specificity.- Distribution of Dipeptidyl Peptidase Iv-Like Activity Enzymes in Canine and Porcine Tissue Sections by RT-PCR.- Metabolic Disorders.- Relative Contribution of Incretins to the Glucose Lowering Effect of DP IV Inhibitors in Type 2 Diabetes Mellitus (T2DM).- Dipeptidyl Peptidase IV: A Molecular Switch of Vascular Actions of Neuropeptide Y.- Immune Disorders.- Dipeptidylpeptidase IV (DPIV) and Alanyl-Aminopeptidases (AAPs) as a New Target Complex for Treatment of Autoimmune and Inflammatory Diseases-Proof of Concept in a Mouse Model of Colitis.- Dipeptidyl Peptidases and Inflammatory Bowel Disease.- Possible Role of DP IV Inhibitors in Acne Therapy.- Dipeptidyl Peptidase-IV Activity and/or Structure Homologs (DASH): Contributing Factors in the Pathogenesis of Rheumatic Diseases?.- Neuronal Diseases.- Dipeptidyl Peptidase IV (DP IV, CD26) and Aminopeptidase N (APN, CD13) as Regulators of T Cell Function and Targets of Immunotherapy in CNS Inflammation.- CD26/DP IV in T Cell Activation and Autoimmunity.- Cancer.- DPIV/CD26 and FAP in Cancer: A Tale of Contradictions.- Type-II Transmembrane Prolyl Dipeptidases and Matrix Metalloproteinases in Membrane Vesicles of Active Endothelial Cells.- Extra-Enzymatic Roles of DPIV and FAP in Cell Adhesion and Migration on Collagen and Fibronectin.- Role of Neuropeptide Y and Dipeptidyl Peptidase IV in Regulation of Ewing's Sarcoma Growth.- The Role of CD26/DPP IV in Preservation of Early Pulmonary Graft Function.
「Nielsen BookData」 より