Infection and inflammation : impacts on oncogenesis

書誌事項

Infection and inflammation : impacts on oncogenesis

volume editors, Thomas Dittmar, Kurt S. Zaenker, Axel Schmidt

(Contributions to microbiology, v. 13)

Karger, 2006

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注記

Includes bibliographical references and index

Memoriam contains some German text

HTTP:URL=http://www.loc.gov/catdir/toc/ecip064/2005035136.html Information=Table of contents

収録内容

  • In remembrance of Rudolf Virchow (1821-1902) / Schmidt, A.
  • In memoriam of Rudolf Virchow: a historical retrospective including aspects of inflammation, infection and neoplasia / Schmidt, A., Weber, O.F.
  • Aneuploidy and cancer: from correlation to causation / Duesberg, P. ... [et al.]
  • Adult stem cell theory of the multi-stage, multi-mechanism theory of carcinogenesis: role of inflammation on the promotion of initiated stem cells / Trosko, J.E., Tai, M.-H.
  • Helicobacter pylori and gastric neoplasia / Leung, W.K.
  • Schistosomiasis and neoplasia / Yosry, A.
  • Relevant oncogenic viruses in veterinary medicine: original pathogens and animal models for human disease / Truyen, U., L"chelt, M.
  • The inflammatory tumor microenvironment and its impact on cancer development / de Visser, K.E., Coussens, L.M.
  • Co-opting macrophage traits in cancer progression: a consequence of tumor cell fusion? / Pawelek, J. ... [et al.]
  • Carcinogenesis driven by bone marrow-derived stem cells / Dittmar, T. ... [et al.]
  • Chemokine-directed metastasis / Gomperts, B.N., Strieter, R.M.
  • Involvement of chemokine receptors in organ-specific metastasis / Zlotnik, A.
  • Visualization of tumor cell extravasation / Heyder, C. ... [et al.]
  • Options for visualizing metastatic disease in the living body / Helms, M.W., Brandt, B.H., Contag, C.
  • Infection, inflammation and neoplasia: an interdisciplinary challenge / Zaenker, K.S

内容説明・目次

内容説明

The last two decades have shown that the local microenvironment plays a pivotal role in cancer progression. Cancer is not the result of mutation events in single cells, but of a complex interplay of tumor cells, inflammatory cells, stem cells, growth factors, cytokines, chemokines and DNA-damaging agents. This book provides an up-to-date overview of how infections and chronic inflammatory conditions can give rise to the onset of a malignant phenotype, a theory that was originally postulated by Rudolf Virchow as early as 1863. Internationally recognized experts discuss novel aspects such as the role of stem cells and the occurrence of aneuploidy in carcinogenesis. Several examples of pathogens and their correlation with specific cancer types are described, e.g. Helicobacter pylori and gastric neoplasia, and schistosomiasis and bladder cancer. The mechanisms of carcinogenesis are examined in detail as are the types of cells that can transform to a malignant phenotype, with special emphasis on stem cells which have recently been shown to give rise to cancer. Further chapters discuss the role of chemokines in directing metastasis and describe options for visualizing metastasis formation in 3-dimensional model systems and in the living body. Our increasing knowledge of the inflammatory microenvironment's role in the carcinogenic process will be the basis for investigating new anti-inflammatory strategies to counter tumor formation and growth. Therefore, this book is essential reading for scientists and clinicians working in cancer research and prevention.

目次

  • In Remembrance of Rudolf Virchow (1821 - 1902): Schmidt, A.
  • Foreword: Dittmar, T.
  • Zaenker, K.S.
  • Schmidt, A.
  • General Aspects
  • In Memoriam of Rudolf Virchow: A Historical Retrospective Including Aspects of Inflammation, Infection and Neoplasia: Schmidt, A.
  • Weber, O.F.
  • Aneuploidy and Cancer: From Correlation to Causation: Duesberg, P.
  • Li, R.
  • Fabarius, A.
  • Hehlmann, R.
  • Adult Stem Cell Theory of the Multi-Stage, Multi-Mechanism Theory of Carcinogenesis: Role of Inflammation on the Promotion of Initiated Stem Cells: Trosko, J.E.
  • Tai, M.-H.
  • Specific Pathogens
  • Helicobacter pylori and Gastric Neoplasia: Leung, W.K.
  • Schistosomiasis and Neoplasia: Yosry, A.
  • Relevant Oncogenic Viruses in Veterinary Medicine: Original Pathogens and Animal Models for Human Disease: Truyen, U.
  • Lochelt, M.
  • Infection, Inflammation and Neoplasia
  • The Inflammatory Tumor Microenvironment and Its Impact on Cancer Development: de Visser, K.E.
  • Coussens, L.M.
  • Co-opting Macrophage Traits in Cancer Progression: A Consequence of Tumor Cell Fusion?: Pawelek, J.
  • Chakraborty, A.
  • Lazova, R.
  • Yilmaz, Y.
  • Cooper, D.
  • Handerson, T.
  • Carcinogenesis Driven by Bone Marrow-Derived Stem Cells: Dittmar, T.
  • Seidel, J.
  • Zaenker, K.S.
  • Niggemann, B.
  • Chemokine-Directed Metastasis
  • Chemokine-Directed Metastasis: Gomperts, B.N.
  • Strieter, R.M.
  • Involvement of Chemokine Receptors in Organ-Specific Metastasis: Zlotnik, A.
  • Visualization of Tumor Cell Extravasation: Heyder, C.
  • Gloria-Maercker, E.
  • Hatzmann, W.
  • Zaenker, K.S.
  • Dittmar, T.
  • Options for Visualizing Metastatic Disease in the Living Body: Helms, M.W.
  • Brandt, B.H.
  • Contag, C.H.
  • Outlook and Perspectives
  • Infection, Inflammation and Neoplasia: An Interdisciplinary Challenge: Zaenker, K.S.
  • Author Index
  • Subject Index.

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