Hepatitis delta virus
著者
書誌事項
Hepatitis delta virus
(Current topics in microbiology and immunology, 307)
Springer, c2006
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内容説明・目次
内容説明
Hepatitis delta virus (HDV), which causes severe acute and chronic liver disease, was discovered nearly 30 years ago following the detection of a novel antigen-antibody system in hepatitis B virus carriers. HDV has continued to surprise and fascinate medical science ever since. This volume reviews recent developments in HDV research, from molecular virology to genetics to experimental investigation of new therapeutic and vaccine candidates.
目次
Structure and Replication of HDV RNA.- HDV RNA Replication: Ancient Relic or Primer?- HDV Ribozymes.- RNA Editing in Hepatitis Delta Virus.- Post-translational Modification of Delta Antigen of Hepatitis D Virus.- The Role of the HBV Envelope Proteins in the HDV Replication Cycle.- Prenylation of HDAg and Antiviral Drug Development.- Hepatitis Delta Virus Variability: from Genotypes I, II, III to 8 M Major Clades?- Functional and Clinical Significance of Hepatitis D Virus Genotype II Infection.- Immunology of HDV Infection.- The Woodchuck Model of HDV Infection.- Subject Index
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