Platelet function : assessment, diagnosis, and treatment

著者

書誌事項

Platelet function : assessment, diagnosis, and treatment

edited by Martin Quinn, Desmond Fitzgerald

（Contemporary cardiology）

Humana Press, c2005

大学図書館所蔵 件 / 全3件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

A cutting-edge review of the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed.

目次

Part I. Platelet Physiology Platelet Physiology Martin Quinn Platelet Integrins and Signaling Karlheinz Peter Platelet Adhesion Brian Savage and Zaverio M. Ruggeri Structure-Function of the Platelet Cytoskeleton Elaine L. Bearer Platelets and Inflammation Meinrad Gawaz Platelet Signal-Dependent Protein Synthesis Stephan Lindemann, Thomas M. McIntyre, Stephen M. Prescott, Guy A. Zimmerman, and Andrew S. Weyrich Phosphoproteomics of Human Platelets Katrin Marcus and Helmut E. Meyer Part II. Assessing Platelet Function Platelet Function Studies Dermot Cox Platelet Function Under Flow Jose A. Lopez, Ian del Conde, and Jing-Fei Dong Pharmacodynamics of GPIIb-IIIa Receptor Blockade Lisa K. Jennings and Melanie M. White Prostanoid Generation in Platelet Function: Assessment and Clinical Relevance Bianca Rocca and Carlo Patrono Platelets and Prothrombin Michael Kalafatis, Emil Negrescu, Tatiana Byzova, and Edward F. Plow Markers of Platelet Activation and Granule Secretion Alan D. Michelson and Mark I. Furman Genomic and Proteomic Analysis of Platelets: Clinical Applications Andrew Maree and James McRedmond Part III. Clinical Applications Antiplatelet Agents Jacqueline Saw and David J. Moliterno Assessing Platelet Function in Clinical Trials Neal Kleiman Index

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