Risk-sharing in the pharmaceutical industry : the case of out-licensing
著者
書誌事項
Risk-sharing in the pharmaceutical industry : the case of out-licensing
（Contributions to management science）
Physica, c2006
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注記
"With 70 figures and 10 tables" -- T.p
内容説明・目次
内容説明
The productivity in pharmaceutical research and development faces intense pres sure. R&D expenditures of the major US and European companies have topped US$ 33 billion in 2003 compared to around US$ 13 billion just a decade ago. At the same time, the number of new drug approvals has dropped from 53 in 1996 to only 35 in 2003. Moreover, the protraction of clinical trials has significantly reduced the effective time of patent protection. The consequences are devastating. Monopoly profits have started to decline and the average costs per new drug have reached a re cord level of close to US$ 1 billion today. As a result, any failure of a new sub stance in the R&D process can lead to considerable losses, and the risks of introduc ing a new drug to the market have grown tremendously. Particularly if a company is highly dependent on just a handful of mega-selling blockbuster drugs, the risks can be even greater. For example, Pfizer generated about 90% of its worldwide revenues in 2002 with just 8 products. Any shortfall of a promising late-stage drug candidate would have left Pfizer with a gaping hole in its product portfolio. In order to deal with these risks, many pharmaceutical companies have started to organize their R&D in partnership. In fact, more than 600 alliances in pharmaceutical R&D are signed every year.
目次
Key Issues in Managing Pharmaceutical Innovation.- Risk-sharing as New Paradigm in Pharma R&D Collaborations.- Case Studies on Risk-sharing in Pharma R&D Collaborations.- Characteristics of Risk-sharing in Pharma R&D Collaborations.- Theoretical Basis for Risk-sharing in Pharma R&D Collaborations.- Managerial Recommendations for Risk-sharing in Pharma R&D Collaborations.- Conclusion.
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