Bibliographic Information

Parasites and allergy

volume editors Monique Capron, François Trottein

(Chemical immunology and allergy / series editors, Johannes Ring, Luciano Adorini, Claudia Berek, Vol. 90)

Karger, 2006

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Description and Table of Contents

Description

The inverse correlation between allergic diseases and helminth infections has been debated for over 30 years. It was initially assumed that the underlying mechanism is an imbalance between Th1 and Th2 responses that, as a result of reduced exposure to Th1-inducing infectious pathogens, has tipped to allergic Th2 responses. It has only recently been clearly demonstrated that helminth infections have negative effects on allergic disease manifestation. This was shown to be consistent with the activity of regulatory cell populations, which control the effector mechanisms of both Th1 and Th2. In this book, international experts in the field discuss the various roles of the cell populations involved in allergic reactions and helminth infections such as regulatory T and B cells, natural killer T cells, mast cells and basophils. Essential for specialists and students in the field, the contributions to this volume pave the way to new directions of research for the successful immunization against helminths and the prevention of inflammatory responses in allergic and autoimmune diseases.

Table of Contents

  • Foreword
  • Helminth-Induced Immunoregulation of an Allergic Response to Food: Nagler-Anderson, C.
  • The Mutual Influence of Nematode Infection and Allergy: Negrao-Correa, D.
  • Teixeira, M.M.
  • Human Schistosomiasis Decreases Immune Responses to Allergens and Clinical Manifestations of Asthma: Araujo, M.I.
  • de Carvalho, E.M.
  • Proteases in Helminth- and Allergen-Induced Inflammatory Responses: Donnelly, S.
  • Dalton, J.P.
  • Loukas, A.
  • Mechanisms Underlying Helminth-Induced Th2 Polarization: Default, Negative or Positive Pathways?: Jankovic, D.
  • Steinfelder, S.
  • Kullberg, M.C.
  • Sher, A.
  • Regulation of Dendritic Cell Function by Pathogen-Derived Molecules Plays a Key Role in Dictating the Outcome of the Adaptive Immune Response: Pearce, E.J.
  • Kane, C.M.
  • Sun, J.
  • Glycans Modulate Immune Responses in Helminth Infections and Allergy: van Die, I.
  • Cummings, R.D.
  • Role of the Natural Killer T Lymphocytes in Th2 Responses during Allergic Asthma and Helminth Parasitic Diseases: Trottein, F.
  • Mallevaey, T.
  • Faveeuw, C.
  • Capron. M.
  • Leite-de-Moraes, M.
  • The Mast Cell and Gut Nematodes: Damage and Defence: Pennock, J.L.
  • Grencis, R.K.
  • Basophils, Basophilia and Helminth Infections: Mitre, E.
  • Nutman, T.B.
  • Innate, Adaptive and Regulatory Responses in Schistosomiasis: Relationship to Allergy: Hartgers, F.C.
  • Smits, H.H.
  • van der Kleij, D.
  • Yazdanbakhsh, M.
  • Regulatory T Cells Induced by Parasites and the Modulation of Allergic Responses: Wilson, M.S.
  • Maizels, R.M.
  • Author and Subject Index.

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