The Therapeutic potential of marihuana
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書誌事項
The Therapeutic potential of marihuana
Plenum Medical Book Co., c1976
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注記
Includes bibliographies and index
内容説明・目次
内容説明
Scientific information about cannabis and its components has grown exponentially during the past decade. Certain of the findings have led to exploratory studies into the therapeutic utility of the drug. At the present time, a number of areas of usefulness have been investigated, with some showing greater promise than others. At what point should these data be collected and presented? Should it be early, after some initial impressions have been obtained? Or should it come later, following confirmatory studies by others? Both stages of development are represented in this volume. In a number of instances, the papers consist of hitherto unpublished material. It seemed worthwhile to bring together the investigators working in a wide variety of disciplines who had in common their research activities in the therapeutic aspects of the cannabinoids and related synthetic compounds. This was done at the Asilomar Conference Center in Pacific Grove, California during November, 1975. The papers presented and the ensuing discussion constitute the contents of this volume. It is the Editors' hope that the book will stimulate further involvement in the therapeutic studies.
It should not be expected, nor is it anticipated that some cannabinoid will be available commercially in the near future. The nature of the approval process is such that years elapse between initial testing, however promising, and final approval for marketing. This is particularly true for a completely new chemical entity, and even more so for one with a checkered reputation.
目次
1. Cross-cultural Perspectives on Therapeutic Uses of Cannabis.- 2. Prostaglandins and Cannabis - IV: A Biochemical Basis for Therapeutic Applications.- 3. On the Therapeutic Possibilities of Some Cannabinoids.- Ophthalmic Effects.- 4. Ocular Effects of Delta-9-Tetrahydrocannabinol.- 5. Experiences with Administration of Marihuana to Glaucoma Patients.- 6. The Effect of Delta-9-Tetrahydrocannabinol on Intraocular Pressure in Humans.- Discussion.- Pulmonary and Preanesthetic Effects.- 7. Bronchial Effects of Aerosolized Delta-9-Tetrahydrocannabinol.- 8. Airways Response to Aerosolized Delta-9-Tetrahydrocannabinol: Preliminary Report.- 9. Respiratory and Cardiovascular Effects of Delta-9-Tetrahydrocannabinol Alone and in Combination with Oxymorphone, Pentobarbital, and Diazepam.- Discussion.- Mental Functioning.- 10. Stimulant Effects of Marihuana on Three Neuropsychological Systems.- 11. Hypnotic Properties of THC: Experimental Comparison of THC, Chloral Hydrate, and Placebo.- 12. The Effect of Beta-adrenergic Blockade on Acute Marihuana Intoxication.- 13. The Use of Marihuana in the Treatment of Alcoholism.- Discussion.- 14. The Therapeutic Aspects of Marihuana: Computer Analyses of Electroencephalographic Data from Human Users of Cannabis Sativa.- 15. Marihuana, Cognitive Style, and Lateralized Hemispheric Functions.- 16. Subjective Benefits and Drawbacks of Marihuana and Alcohol.- 17. Marihuana and Human Cognition: A Review of Laboratory Investigations.- Discussion.- Tumor Problems.- 18. Analgesic and Antitumor Potential of the Cannabinoids.- 19. Treatment Effects of Delta-9-THC in an Advanced Cancer Population.- 20. Antiemetic Effect of Delta-9-Tetrahydrocannabinol in Patients Receiving Cancer Chemotherapy.- Discussion.- Anticonvulsant Activity.- 21. Marihuana and Epilepsy: Activation of Symptoms by Delta-9-THC.- 22. Anticonvulsant-Convulsant Effects of Delta-9-Tetrahydrocannabinol.- 23. The Antiepileptic Potential of the Cannabinoids.- Discussion.- Synthetic Cannabinoid-Like Compounds.- 24. Clinical Pharmacology of Natural and Synthetic Cannabinoids.- 25. Heterocyclic Analogs of the Cannabinoids.- 26. Preclinical Neuropharmacology of Three Nitrogen-Containing Heterocyclic Benzopyrans Derived from the Cannabinoid Nucleus.- 27. Comparative Toxicities of Tetrahydropyridobenzopyrans.- 28. New Benzopyrans: Anticonvulsant Activities.- Discussion.- Conclusions of the Conference.- Speakers and Section Chairmen.- Those in Attendance other than Speakers.
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