Rise and fall of epithelial phenotype : concepts of epithelial-mesenchymal transition
著者
書誌事項
Rise and fall of epithelial phenotype : concepts of epithelial-mesenchymal transition
(Molecular biology intelligence unit)
Landes Bioscience/Eurekah.com , Kluwer Academic/Plenum Publishers, c2005
大学図書館所蔵 全3件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT).
The Rise and Fall of Epithelial Phenotype is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.
目次
EMT Concept and Examples from the Vertebrate Embryo.- Epithelium-Mesenchyme Transitions Are Crucial Morphogenetic Events Occurring during Early Development.- The Neural Crest.- Epithelial-Mesenchymal Transformation in the Embryonic Heart.- Epithelial-Extracellular Matrix (Cell-ECM) Interactions in Hydra.- Regulation of the Epithelial-to-Mesenchymal Transition in Sea Urchin Embryos.- Change of Epithelial Fate.- Cutaneous Wound Reepithelialization.- Epithelial-Mesenchymal Transitions in Human Cancer.- Structural and Functional Regulation of Desmosomes.- Epithelial Cell Plasticity by Dynamic Transcriptional Regulation of E-Cadherin.- The Regulation of Catenins in Cancer.- Hepatocyte Growth Factor Regulates Transitions between Epithelial and Mesenchymal Cellular Phenotypes during Normal Development and in Disease.- The Role of Insulin-Like Growth Factors in the Epithelial to Mesenchymal Transition.- TGF?-Dependent Epithelial-Mesenchymal Transition.- The Ras and Src Signaling Cascades Involved in Epithelial Cell Scattering.- Regulation of E-Cadherin-Mediated Cell-Cell Adhesion by Rho Family GTPases.- Wnt Signaling Networks and Embryonic Patterning.- Cadherin-Mediated Cell-Cell Adhesion and the Microtubule Network.- Matrix Metalloproteases and Epithelial-to-Mesenchymal Transition.
「Nielsen BookData」 より