Herpes zoster : recent aspects of diagnosis and control


Herpes zoster : recent aspects of diagnosis and control

volume editors, Gerd Gross, Hans-Wilhelm Doerr

(Monographs in virology, v. 26)

Karger, c2006

  • hard cover

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Includes bibliographical references and index



Herpes zoster (shingles) is a serious neurocutaneous disease caused by a reactivation of latent varicella-zoster virus (VZV). It has been underestimated in terms of its burden, particularly in the elderly population and in immunocompromised patients, who can develop severe complications such as postherpetic neuralgia, meningitis or optic nerve damage. This book compiles state-of-the-art reviews on herpes zoster and VZV by leading clinicians and researchers in the field. They cover the molecular biology, latency and reactivation of the virus as well as the diagnosis, clinical manifestations, epidemiology and therapy of VZV infection. Infections in high-risk patients (immunocompromised hosts and bone marrow recipients) and pregnant women are considered in detail. Emphasis is also given to the direction of future research efforts which will be focused on the very early prevention of chronic zoster pain by combined antiviral and analgesic therapy, and on the control of herpes zoster by administering a VZV-specific vaccine. Providing a valuable update on current strategies to diagnose, treat and prevent herpes zoster, this book is of special interest to clinical virologists, dermatologists, neurologists, gerontologists, pediatricians, ophthalmologists, otologists and general physicians.


  • Preface
  • Virology and Laboratory Investigations
  • Molecular Biology of Varicella-Zoster Virus: Rahaus, M.
  • Desloges, N.
  • Wolff, M.H.
  • Latency and Reactivation of VZV: Lungu, O.
  • Gershon, A.A.
  • Laboratory Confirmation of Herpes Zoster: Ludwig, B.
  • Buxbaum, S.
  • Doerr, H.W.
  • Spectrum of Clinical Manifestations and Outcome
  • Clinical Picture and Complications of Herpes Zoster: The View of the Dermatologist: Gross, G.
  • Ophthalmic Manifestations of Herpes Zoster Infection: Guembel, H.
  • (Herpes) Zoster Oticus: Pau, H.W.
  • Neuroanatomy of Pain and Neuropathology of Herpes Zoster and Postherpetic Neuralgia: Wree, A.
  • Schmitt, O.
  • Usunoff, K.G.
  • Postherpetic Neuralgia and other Neurologic Complications: Baron, R.
  • Varicella-Zoster Virus Infections during Pregnancy: Sauerbrei, A.
  • Wutzler, P.
  • Herpes Zoster in the Immunocompromised Host: Schofer, H.
  • Chickenpox and Zoster in Marrow Transplant Recipients: Genvresse, I.
  • Maschmeyer, G.
  • Therapy
  • General Aspects of Therapy: Gross, G.
  • Antiviral Therapy of Shingles in Dermatology: Lilie, H.M.
  • Wassilew, S.W.
  • Highly Potent and Selective Inhibition of Varicella-Zoster Virus Replication by Bicyclic Furo[2,3-d] pyrimidine Nucleoside Analogues (BCNAs): De Clercq, E.
  • Therapy of Zoster Pain, Postherpetic Neuralgia and Other Neurological Complications: Baron, R.
  • Epidemiology and Control of Herpes Zoster
  • Epidemiology of Herpes Zoster: What has Changed?: Allwinn, R.
  • Buxbaum, S.
  • Doerr, H.W.
  • Live Attenuated Varicella Vaccine: Gershon, A.A.
  • Appendix
  • Subject Index.

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