Molecular genetics, gastrointestinal carcinoma, and ovarian carcinoma
著者
書誌事項
Molecular genetics, gastrointestinal carcinoma, and ovarian carcinoma
(Handbook of immunohistochemistry and in situ hybridization of human carcinomas / edited by M.A. Hayat, v. 4)
Elsevier Academic Press, c2006
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注記
Includes index
内容説明・目次
内容説明
Classical histology has been augmented by
immunohistochemistry (the use of specific antibodies to stain particular molecular species in situ). Immunohistochemistry has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system.
This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method.
目次
Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas
Front Matter
Dedication
Authors and Coauthors of Volume 4
Foreword
Preface
Selected Definitions
Classification Scheme of Human Cancers
Identification of Tumor-Specific Genes
The Post-Translational Phase of Gene Expression in Tumor Diagnosis
Role of Tumor Suppressor BARD1 in Apoptosis and Cancer
Angiogenesis, Metastasis, and Epigenetics in Cancer
Can Effector Cells Really aEUROoeEffectaEURO an Anti-Tumor Response as Cancer Therapy?
Circulating Cancer Cells
Circulating Cancer Cells: Flow Cytometry, Video Microscopy, and Confocal Laser Scanning Microscopy
Gastrointestinal Carcinoma: An Introduction
Role of Immunohistochemical Expression of p53 in Gastric Carcinoma
Role of Immunohistochemical Expression of p53 and Vascular Endothelial Growth Factor in Gastric Carcinoma
Role of Immunohistochemical Expression of p150 in Gastric Carcinoma: The Association with p53, Apoptosis, and Cell Proliferation
Role of Immunohistochemical Expression of Ki-67 in Adenocarcinoma of Large Intestine
Role of Immunohistochemical Expression of KIT/CD117 in Gastrointestinal Stromal Tumors
Role of Immunohistochemical Expression of BUB1 Protein in Gastric Cancer
Role of Immunohistochemical Expression of Epidermal Growth Factor in Gastric Tumors
Role of Immunohistochemical Expression of Beta-Catenin and Mucin in Stomach Cancer
Loss of Cyclin D2 Expression in Gastric Cancer
Role of Immunohistochemical Expression of E-Cadherin in Diffuse-Type Gastric Cancer
Role of Immunohistochemical Expression of Adenomatous Polyposis Coli and E-Cadherin in Gastric Carcinoma
Immunohistochemical Expression of Chromogranin A and Leu-7 in Gastrointestinal Carcinoids
Role of Immunohistochemical Expression of MUC5B in Gastric Carcinoma
Angiogenin in Gastric Cancer and Its Roles in Malignancy
Role of Helicobacter pylori in Gastric Cancer
Protein Alterations in Gastric Adenocarcinoma
Vesicle Proteins in Neuroendocrine and Nonendocrine Tumors of the Gastrointestinal Tract
Role of Immunohistochemical Expression of Caspase-3 in Gastric Carcinoma
Role of Immunohistochemical Expression of PRL-3 Phosphatase in Gastric Carcinoma
Role of Immunohistochemical Expression of DNA Methyltransferase 1 Protein in Gastric Carcinoma
Role of Immunohistochemical Expression of Cytoplasmic Trefoil Factor Family-2 in Gastric Cancer
Role of Immunohistochemical Expression of Cytokeratins in Small Intestinal Adenocarcinoma
Quantitative Immunohistochemistry by Determining the Norm of the Image Data File
Ovarian Carcinoma: An Introduction
Methods for Detecting Genetic Abnormalities in Ovarian Carcinoma Using Fluorescence in situ Hybridization and Immunohistochemistry
Role of Immunohistochemical Expression of HER2/neu in High-Grade Ovarian Serous Papillary Cancer
Role of Immunohistochemical Expression of BRCA1 in Ovarian Carcinoma
Role of BRCA1/BRCA2 in Ovarian, Fallopian Tube, and Peritoneal Papillary Serous Carcinoma
K-Ras Mutations in Serous Borderline Tumors of the Ovary
Role of Immunohistochemical Expression of Ki-67 in Ovarian Carcinoma
Role of Expression of Estrogen Receptor I(2), Proliferating Cell Nuclear Antigen, and p53 in Ovarian Granulosa Cell Tumors
Role of Immunohistochemical Expression of Cyclooxygenase-2 in Ovarian Serous Carcinoma
Role of Immunohistochemical Expression of Cyclooxygenase and Peroxisome ProliferatoraEURO"Activated Receptor I(3) in Epithelial Ovarian Tumors
CDX2 Immunostaining in Primary and Secondary Ovarian Carcinomas
Epithelial Ovarian Cancer and the E-CadherinaEURO"Catenin Complex
Role of Cytokeratin Immunohistochemistry in the Differential Diagnosis of Ovarian Tumors
Role of Immunohistochemical Expression of Cytokeratins and Mucins in Ampullary Carcinomas
Role of Integrins in Ovarian Cancer
Role of Immunohistochemical Expression of Vascular Endothelial Growth Factor C and Vascular Endothelial Growth Factor Receptor 2 in Ovarian Cancer
Use of Microarray in Immunohistochemical Localization of SMAD in Ovarian Carcinoma
Role of Immunohistochemical Expression of Fas in Ovarian Carcinoma
Role of Immunohistochemical Expression of Lewis Y Antigen in Ovarian Carcinoma
Role of Immunohistochemical Expression of ETS-1 Factor in Ovarian Carcinoma
Role of MCL-1 in Ovarian Carcinoma
Role of Elf-1 in Epithelial Ovarian Carcinoma: Immunohistochemistry
Role of Immunohistochemical Expression of OCT4 in Ovarian Dysgerminoma
Immunohistochemical Validation of B7-H4 (DD-O110) as a Biomarker of Ovarian Cancer: Correlation with CA-125
Role of Immunohistochemical Expression of Alpha Glutathione S-Transferase in Ovarian Carcinoma
Role of Immunohistochemical Expression of Aminopeptidases in Ovarian Carcinoma
Expression of Angiopoietin-1, Angiopoietin-2, and Tie2 in Normal Ovary with Corpus Luteum and in Ovarian Carcinoma
The Role of Immunohistochemical Expression of 1,25-Dihydroxyvitamin-D3-Receptors in Ovarian Carcinoma
Role of Immunohistochemical Expression of Antigens in Neuroendocrine Carcinoma of the Ovary and Its Differential Diagnostic Considerations
Role of Immunohistochemistry in Elucidating Lung Cancer Metastatic to the Ovary from Primary Ovarian Carcinoma
Index
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