Introduction to computational genomics : a case studies approach
著者
書誌事項
Introduction to computational genomics : a case studies approach
Cambridge University Press, 2007
- : hbk
- : pbk
大学図書館所蔵 全10件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Bibliography: p. 173-178
Includes index
内容説明・目次
内容説明
Where did SARS come from? Have we inherited genes from Neanderthals? How do plants use their internal clock? The genomic revolution in biology enables us to answer such questions. But the revolution would have been impossible without the support of powerful computational and statistical methods that enable us to exploit genomic data. Many universities are introducing courses to train the next generation of bioinformaticians: biologists fluent in mathematics and computer science, and data analysts familiar with biology. This readable and entertaining book, based on successful taught courses, provides a roadmap to navigate entry to this field. It guides the reader through key achievements of bioinformatics, using a hands-on approach. Statistical sequence analysis, sequence alignment, hidden Markov models, gene and motif finding and more, are introduced in a rigorous yet accessible way. A companion website provides the reader with Matlab-related software tools for reproducing the steps demonstrated in the book.
目次
- Prologue (in praise of cells)
- 1. The first look at a genome (sequence statistics)
- 2. All the sequence's men (gene finding)
- 3. All in the family (sequence alignment)
- 4. The boulevard of broken genes (hidden Markov models)
- 5. Are Neanderthals among us? (variation within and between species)
- 6. Fighting HIV (natural selection at the molecular level)
- 7. SARS: a post-genomic epidemic (phylogenetic analysis)
- 8. Welcome to the hotel Chlamydia (whole genome comparisons)
- 9. The genomics of wine-making (analysis of gene expression)
- 10. A bed-time story (identification of regulatory sequences)
- Appendix.
「Nielsen BookData」 より