Alzheimer's Disease : Advances in Genetics, Molecular and Cellular Biology
Author(s)
Bibliographic Information
Alzheimer's Disease : Advances in Genetics, Molecular and Cellular Biology
Springer, 2007
Available at / 3 libraries
-
No Libraries matched.
- Remove all filters.
Note
Includes bibliographical references (p. 271-277) and index
Description and Table of Contents
Description
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.
Table of Contents
The Genetics of Alzheimer's Disease.- APP Biology, Processing and Function.- The Biology of the Presenilin Complexes.- ?-secretase: Physiological Role and Target Validation.- Cognitive Impairment in Transgenic A? and Tau Models of Alzheimer's Disease.- Cholesterol and ?-Amyloid.- A? Structure and Aggregation.- Signaling Mechanisms that Mediate A? Induced Neuronal Dysfunction.- Beta Amyloid and Excitatory Synapses.- A? Degradation.- Role of A ? Transport and Clearance in the Pathogenesis and Treatment of Alzheimer's Disease.- Tau Gene Mutations in FTDP-17 Syndromes.- Animal Models of Tauopathy.- Tau and Axonal Transport.- Growth Factors in Alzheimer's Disease.
by "Nielsen BookData"