Structure-based Drug Discovery
Author(s)
Bibliographic Information
Structure-based Drug Discovery
Springer, c2007
- : hbk
- : [pbk.]
Available at / 9 libraries
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Hokkaido University, Library, Graduate School of Science, Faculty of Science and School of Science図書
: hbk615.19/J5592080221715
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Note
Bibliography: p. 239-245
Description and Table of Contents
Description
This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.
Table of Contents
Five Years of Increasing Structural Biology Throughput - A Retrospective Analysis.- Protein Production for Structural Genomics - Strategies for the Next Phase.- to Fragment Screening.- Fragment-Based NMR Screening in Lead Discovery.- Fragment-Based Screening by X-ray Crystallography.- Scaffold-Based Drug Discovery.- Biophysical Methods.- Illustration of Current Challenges in Molecular Docking.- Scoring Functions.
by "Nielsen BookData"