Structure-based Drug Discovery

Author(s)

    • Jhoti, Harren
    • Leach, Andrew

Bibliographic Information

Structure-based Drug Discovery

edited by Harren Jhoti, Andrew R. Leach

Springer, c2007

  • : hbk
  • : [pbk.]

Available at  / 9 libraries

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Note

Bibliography: p. 239-245

Description and Table of Contents

Description

This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.

Table of Contents

Five Years of Increasing Structural Biology Throughput - A Retrospective Analysis.- Protein Production for Structural Genomics - Strategies for the Next Phase.- to Fragment Screening.- Fragment-Based NMR Screening in Lead Discovery.- Fragment-Based Screening by X-ray Crystallography.- Scaffold-Based Drug Discovery.- Biophysical Methods.- Illustration of Current Challenges in Molecular Docking.- Scoring Functions.

by "Nielsen BookData"

Details

  • NCID
    BA81188378
  • ISBN
    • 1402044062
    • 9789048171231
  • Country Code
    ne
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Dordrecht
  • Pages/Volumes
    xii, 249 p.
  • Size
    25 cm
  • Classification
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