Novel optical resolution technologies
著者
書誌事項
Novel optical resolution technologies
(Topics in current chemistry = Fortschritte der chemischen Forschung, 269)
Springer, c2007
大学図書館所蔵 全10件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ment. Variousphysical methodsare capableofresolvingthesurface as wellas theinsidestructureofcrystalsattheatomiclevelwhilenewhigh-performance computingresourcesaffordthecapabilityofmodelingthecomplexlarge-scale alignmentsnecessarytosimulatecrystallizationinrealsystems.Asaresult,the science of crystallization has shifted gradually fromstatic to dynamic science and considerable progress now underlies the complex but beautiful cryst- lization process. I believe that if a de?nitive history of 21st century science is ever written,one of the highlightswill be the science ofcrystallization. This science has the following characteristics: in?nite advances in soph- tication, unlimited opportunities not only for intellectual excitement but also forindustrialmerit,strongcollaborationwithbiologyandmaterialscience,as wellaswithallareasofchemistry.Thevastpotentialofcrystallizationasan- portant?eld ofscience isfar beyondthesimple technologyofpharmaceutical industries during the 20th century.
Optical resolution was one small area of chemistry in the last century. This was more a technology than a science, largely because trial and error was the only method to obtain good results. However, the situation is now changing. Therearesomanyappealing,hidden?ndingsintheprocessofcrystallization. Historically, crystallization began in an old laboratory in academia and then gradually shifted to industry. Now,it is making itscomeback in academia due toseveralnewresearchbranchestryingtodiscoverwhatisgoingonduringthe crystallizationprocess.Ibelieve this?eld ofscience isnowgrowingasa result of the wonderfulcoupling between industry and academia. I read a prepublication draft of Novel Optical Resolution Technologies,and foundthateachoneofthesegeneralcharacteristicsofsciencehadarealityand sharpness that I had not expected. While it was a sheer delight to revisit each of these triumphs guided by the wise insights and analyses found throughout the book. There is a good balance between the underlying historical material and the design and execution aspects of each topic.
目次
G. Coquerel: Preferential Crystallization.- R. Tamura, H. Takahashi, D. Fujimoto, T. Ushio: Mechanism and Scope of Preferential Enrichment, a Symmetry-Breaking Enantiomeric Resolution Phenomenon.- R. Yoshioka: Racemization, Optical Resolution, and Crystallization-Induced Asymmetric Transformation of Amino Acids and Pharmaceutical Intermediates.- F. Faigl, J. Schindler, E. Fogassy: Advantages of Structural Similarities of the Reactants in Optical Resolution Processes.- R.M. Kellogg , B. Kaptein, T.R. Vries: Dutch Resolution of Racemates and the Roles of Solid Solution Formation and Nucleation Inhibition.- K. Sakai, R. Sakurai, H. Nohira: New Resolution Technologies Controlled by Chiral Discrimination Mechanisms.- K. Sakai, R. Sakurai, N. Hirayama: Molecular Mechanisms of Dielectrically Controlled Resolution (DCR).- H. Murakami: From Racemates to Single Enantiomers - Chiral Synthetic Drugs over the Recent 20 Years
「Nielsen BookData」 より