Neurophysiological monitoring during intensive care and surgery
著者
書誌事項
Neurophysiological monitoring during intensive care and surgery
Elsevier, c2006
大学図書館所蔵 全2件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographic references and index (p. 377-390)
内容説明・目次
内容説明
The principal aim of neurophysiological monitoring is to prevent damage to the nervous system. Achieving this aim places great demands on both personnel and equipment. Traditionally the need for monitoring has been determined by clinicians (surgeons, anaesthetists, intensivists), and it has been provided by clinical neurophysiologists acting as visiting consultants in the operating theatre and intensive care unit. While there can be no doubt that neurophysiological monitoring is vital for the patient at risk of permanent neurological damage, monitoring presents challenging practical problems for anaesthetist and neurophysiologist. On the one hand, the neurophysiologist finds that the level of electrical interference from patient-connected anaesthetic and surgical equipment is an obstacle to recording low amplitude signals from the nervous system; on the other hand, the anaesthetist may be asked to avoid neuromuscular blocking drugs and powerful anaesthetic agents, so that the task of keeping the patient asleep and immobile is more difficult. These competing requirements should be approached in a spirit of cooperative teamwork and compromise.
In the intensive care unit neurophysiological recordings can give diagnostic and prognostic information, and sometimes influence treatment. Prolonged monitoring of brain function allows clinicians to recognize spontaneous fluctuations of activity in comatose patients, the arousal responses of inadequately sedated patients, and the previously unrecognized incidence of epileptiform activity, particularly after head injury or neurosurgical procedures. For these reasons neurophysiological monitoring is being used more often in general as well as neuro-intensive care units. During surgical operations monitoring has been used at the request of the surgeon to detect impending damage to neural pathways, the onset of ischaemia, and the development of epileptiform discharges. In addition, the possibility of unintentional awareness has now become an important legal issue for anaesthetists, and any means of avoiding it is warmly welcomed.
As a result of the great increase in power of readily-available computers in the 1990s, monitoring devices began to appear which extracted certain characteristics of the EEG or an EP, and in some cases compressed them into a single number thought to indicate clinically important states of the nervous system. Enthusiastic marketing ensured that anaesthetists and surgeons became interested in brain waves; now they had a box to tell the anaesthetist how close the patient was to awareness, or at least that was what the makers claimed it could do. As often happens following the introduction of new technology, clinicians were divided into the enthusiasts, the sceptics, and those waiting for compelling evidence before deciding one way or the other. According to the enthusiasts, EEG-monitored anaesthesia reduces the incidence of unintentional awareness, shortens recovery time, and makes anaesthesia a pleasanter experience for the patient, who is more alert and less nauseous postoperatively. The enthusiasts therefore advocate monitoring every anaesthetized patient with an EEG or EP index.
Sceptics, on the other hand, point out that some anaesthetic agents do not affect the EEG or EPs in the expected manner, and so render the indices unreliable. Poor electrode application, external electrical interference, and muscle and movement artefacts produce misleading results. Because the indices are validated in normal subjects, they are less reliable, and in some cases useless, in the presence of epileptiform discharges or the EEG patterns produced by encephalopathies. The reluctance of some manufacturers to publish the algorithms underlying their indices has only served to heighten scepticism. The situation is not helped by the fact that few anaesthetists or surgeons are expert in neurophysiology, and merely follow the behaviour of an index number, without understanding the EEG or EP signal from which it is derived; some have even attempted to detect cerebral ischaemia with monitoring devices designed for prevention of awareness. Editors of journals therefore have a particularly difficult task in ensuring that published reports on surgery and anaesthesia monitored by EEG or EPs are of the same scientific standard as those on other subjects.
While EEG and EP monitors undoubtedly have their place in the operating theatre, their precise contribution needs to be clarified. They must not be regarded as replacing conventional EEG or EPs, but merely as indicating the effect upon the brain of clearly defined and rigidly specified anaesthetic and surgical techniques. The inappropriate perioperative use of neurophysiological methods will only be avoided by educating anaesthetists and surgeons. They should not be expected to become neurophysiologists, but they should understand the physiology of neuronal activity, and the basics of signal acquisition and interpretation. In particular, anaesthetists should be encouraged to demand a high quality display of the raw EEG or EP along with a depth-of-anaesthesia index, just This book is derived from the two volumes entitled Clinical Neurophysiology (Binnie et al, 2003, 2004). We have compiled it using material extracted, rearranged and expanded from these parent volumes to cater for the particular needs of those working in neurophysiological monitoring.
Such monitoring in the intensive care unit and the operating theatre has developed into a rapidly expanding subspecialty of clinical neurophysiology, to which many neurophysiologists and their technologists now devote a substantial part of their professional lives. At the same time, it was appreciated that colleagues in other specialties needed to understand what could - and, more important, what could not - be expected from monitoring. Also, in many hospitals, monitoring was being carried out by anaesthetists, surgeons, intensivists and others who lacked a firm grounding in the basics of clinical neurophysiology. There are several important differences between monitoring and other branches of clinical neurophysiology. Firstly, the principal aim of monitoring is to warn of deterioration, and thereby to avoid catastrophe, rather than to provide diagnostic information. Secondly, the population norm is of much less importance because the patient usually serves as his or her own control. Thirdly, monitoring has found applications in many apparently disparate branches of surgery and intensive care, and no one can claim to be expert, or even reasonably competent, in all of them.
We have tried to keep these points in mind in preparing this book, and to provide sufficient explanation of the neurophysiological background for those entering the field from other specialties, including biomedical engineers and medico-legal experts as well as clinicians and clinical scientists. Nevertheless, in many cases the reader is referred to one or other of the parent volumes for an account of the basics; more detailed information on neurophysiological technology is given in Cooper, Binnie and Billings (2005), which provides a convenient companion to this present volume. We are acutely aware that neurophysiological monitoring is still developing rapidly, so that parts of the present volume may soon be out of date, if they are not already. Faced with such an actively developing subject, a printed book is perhaps not the best way of presenting information; an Internet version would provide greater possibilities of regular updating if the demand arises. Finally, we must reiterate the injunction with which the Editors of the parent volumes concluded their Preface.
Although the information in this book is correct to the best of our knowledge, no one should attempt to carry out any of the techniques described without having undertaken adequate, recognized training, and without consulting up-to-date local, national and international safety regulations, and local, national and international recommendations on good practice.
目次
- Contributors, v
- Foreword, vii
- Preface, ix
- Dedication, x
- Acknowledgements, x
- Abbreviations, xi
- 1 The why and the how of neurophysiological monitoring in the ICU and surgery, 1
- Introduction, 1
- Applications of clinical neurophysiology in the ICU, 1
- Monitoring during surgical operations, 3
- Assessment of results, 7
- Statistical significance of changes, 7
- Clinical significance of changes, 8
- Confidence intervals, 10
- Determining the optimal cut-off point, 11
- Comparing two methods of monitoring, 11
- The effect of corrective action, 12
- Is the risk eliminated by monitoring?, 13
- References, 14
- 2 Neurophysiological instrumentation, connection with patients and recording methods, 17
- Introduction, 17
- Recording the electrical activities of the nervous system, 18
- Electrodes for neurophysiological recording, 18
- Electrode placement systems, 24
- Connecting electrodes to amplifiers and the recording convention, 29
- Amplifiers, 32
- Signal bandwidth and filters, 35
- Digital systems, 37
- EEG recording equipment, 38
- General features of EEG machines, 38
- Input circuits for EEG recording, 39
- Amplifiers for EEG recording, 39
- Filters for EEG recording, 40
- Analogue EEG systems, 40
- Digital EEG systems, 42
- Evoked potential recording systems, 48
- Electrodes for EP recording, 48
- Amplifiers for EP recording, 48
- Filters for EP recording, 48
- Averaging, 48
- EP display, 49
- Calibration of EP recorders, 49
- EP stimulators, 49
- EMG and nerve conduction studies, 53
- Electrodes for EMG and nerve conduction studies, 53
- Amplifiers for EMG and nerve conduction, 54
- Displaying EMG and nerve conduction data, 55
- Stimulation for nerve conduction studies, 55
- Practical aspects of intraoperative and ICU neurophysiological recording, 55
- Safety during neurophysiological recording in the ICU and operating theatres, 55
- Intraoperative and ICU EEG recording, 59
- Intraoperative and ICU EP recording, 65
- EMG and nerve conduction studies, 68
- References, 68
- 3 Introduction to methods for continuous EEG and evoked potential monitoring, 73
- Introduction, 73
- EEG monitoring, 73
- Historical development of EEG monitors, 73
- Technical requirements for EEG monitoring in the ICU and during surgical operations, 85
- Evoked potential monitoring, 94
- Technical requirements for EP monitoring, 94
- Comparisons between currently used methods, 100
- Conclusions, 102
- References, 103. 4 Normal and pathological phenomena in EEG, evoked potential, EMG and nerve conduction studies, 109
- General introduction, 109
- EEG WAVEFORMS AND INTERPRETATION, 109
- Introduction, 109
- Describing EEG phenomena, 109
- Wave shape (morphology), 110
- Rhythmicity, 110
- Frequency of repetition, 110
- Amplitude, 110
- Transients, 112
- Spatial distribution, 113
- Spatiotemporal patterns, 113
- Symmetry and synchrony, 113
- Inherent variability of the EEG and other biological rhythms, 113
- Reactivity, 114
- General categories of abnormality in the EEG of importance for ICU and intraoperative monitoring, 114
- Change in frequency content, 114
- Amplitude reduction, 115
- Localized and lateralized abnormalities, 116
- Rhythms at a distance (projected rhythms), 117
- Altered reactivity, 118
- Epileptiform activity, 119
- Periodicity, 120
- Burst suppression pattern, 123
- Electrocerebral inactivity - electrocerebral silence (ECS) - the isoelectric EEG, 124
- EVOKED POTENTIAL WAVEFORMS AND INTERPRETATION, 125
- General definition - limitations - clinical utility of evoked potentials, 125
- Responses and EP components, 126
- The electroretinogram and electrocochleogram, 126
- Relation between neuronal responses and surface evoked potentials, 127
- Action potentials, 127
- Postsynaptic potentials, 128
- Near-field versus far-field evoked potentials, 128
- How to localize evoked potential sources from surface recordings, 130
- Normal findings by modality, 131
- Flash VEPs, 131
- Auditory evoked potentials: BAEPs and MLAEPs, 132
- Somatosensory evoked potentials, 134
- EMG FINDINGS AND INTERPRETATION, 145
- Features of motor units recorded by needle electrodes, 145
- Other normal EEG phenomena, 145
- Insertion activity, 145
- End-plate noise, 145
- Fibrillations at single sites, 146
- Fasciculations, 146
- Nerve conduction, 147
- Effects of limb temperature on nerve conduction, 147
- References, 148
- 5 Neurophysiological monitoring during sedation and anaesthesia, 155
- Introduction, 155
- Sedation: assessment with EEG and evoked potentials, 155
- Effects of sedative drugs on the EEG, 155
- Effects of sedative drugs on EPs, 157
- Assessment of sedation, 159
- Anaesthesia: assessment with EEG and evoked potentials, 161
- Effect of anaesthetic agents on the EEG, 161
- Effect of anaesthetic agents on EPs, 172
- Combined EEG and evoked potential measures, 176
- Awareness during anaesthesia, 176
- Neurophysiological features useful in prediction of possible awareness during anaesthesia, 177
- Medico-legal aspects of awareness during anaesthesia, 180
- References, 182
- 6 Neurophysiological work in the ICU, 189
- Introduction, 189
- Neurophysiological parameters to be monitored and procedures, 189
- Sleep in the ICU, 189
- CLINICAL CONDITIONS AFFECTING THE CENTRAL NERVOUS SYSTEM ENCOUNTERED IN ICU, 189
- Coma and related states, 189
- EEG recording and interpretation in coma and related states, 189
- EPs in comatose patients, 199
- EPs combined with other variables, 215
- Cardiac arrest and hypoxic - ischaemic encephalopathies, 216
- Other metabolic and toxic encephalopathies and multiple organ failure, 218
- Encephalitis, 218
- Epileptiform discharges and status epilepticus, 218
- Head injury and other neurosurgical applications, 221. Vegetative states and brainstem death (brain death), 225
- Vegetative states, 225
- Brainstem death (brain death), 228
- CLINICAL CONDITIONS AFFECTING THE PERIPHERAL NERVOUS SYSTEM AND MUSCLES ENCOUNTERED IN THE ICU, 231
- Neuromuscular syndromes of critical illness (critical illness neuropathy), 231
- Acute onset neuropathies, 234
- Guillain - Barre syndrome (GBS), 234
- Acute intermittent porphyria, 237
- Other causes of acute or subacute peripheral neuropathy, 242
- Acute weakness due to disorders of neuromuscular transmission, 242
- Botulism, 242
- Myasthenia gravis, 242
- Familial periodic paralysis and the channelopathies, 242
- Non-peripheral causes of acute onset generalized weakness, 243
- References, 243
- 7 Neurophysiological monitoring during surgical operations, 253
- Introduction, 253
- Intracranial surgery, 253
- EEG monitoring in intracranial surgery, 253
- Visual evoked potential monitoring, 256
- SEP monitoring in intracranial surgery, 257
- Posterior fossa surgery, 260
- Spinal cord function monitoring, 268
- Experimental studies and mechanisms of spinal cord damage, 268
- Methods of monitoring cord function, 269
- Practical aspects of spinal cord monitoring, 272
- Clinical applications of spinal cord monitoring, 274
- Spinal root surgery and peripheral nerve surgery, 278
- Cerebral ischaemia during non-intracranial surgery, 279
- Cardiac surgery, 279
- Carotid endarterectomy, 285
- References, 292
- 8 Further signal analysis, 309
- Introduction, 309
- Data acquisition, 311
- Technology, 311
- Safety issues, 315
- Improving signal quality, 317
- Filtering methods, 318
- Artefact detection and rejection methods, 327
- Signal processing and interpretation, 327
- Common processing tasks, 329
- Processing methods, 332
- Integration of features into the clinical context - pattern classification, 346
- Statistical process control, 354
- Use of the tools, 358
- Decision assistance, 358
- Development and uptake of methods, 359
- Performance assessment, 359
- Display of results, 360
- Use of IT facilities, 363
- References, 365
- 9 Legal implications of neurophysiological monitoring, 371
- Safety of patients and staff, 371
- Electromedical equipment, 372
- Infection control, 373
- Drugs, 373
- Identification of patients and consent to procedures, 373
- Inherent risk of procedures, 374
- Responsibilities in training and supervising staff, 374
- Responsibilities in respect of reports on investigations, 375
- References, 375
- Index, 377.
「Nielsen BookData」 より