The Neuregulin-I/ErbB Signaling System in Development and Disease
著者
書誌事項
The Neuregulin-I/ErbB Signaling System in Development and Disease
(Advances in anatomy, embryology and cell biology, 190)
Springer, c2007
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注記
"With 14 Figures and 2 Tables"
Includes bibliographical references (p. [47]-65) and index
内容説明・目次
内容説明
Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. Neuregulin signals are also involved in the development diseases including breast cancer, heart disease and the pathogenesis of schizophrenia. This book reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease.
目次
Introduction - Molecular control of development.- Biology of the Neuregulin/ErbB signaling network.- Neuregulins and their receptors.- Developmental functions of the Neuregulin-1/ErbB signalling pathway.- Interacting molecules - the Sox10/ErbB connection.- NRG-1/ErbB signals and disease.- Abbreviations.- References.- Subject index
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