T cell activation by CD1 and lipid antigens

著者

• Moody, Branch D

書誌事項

T cell activation by CD1 and lipid antigens

D.B. Moody (ed.)

（Current topics in microbiology and immunology, 314）

Springer Berlin, 2007

内容説明・目次

内容説明

There is increasing evidence that the CD1 system has been conserved throughout mammalian evolution and is capable of presenting structurally diverse diacyglycerol, sphingolipid, polyisoprenol and lipopeptide antigens. This volume provides a comprehensive discussion of these basic aspects of CD1 biology and summarizes the most recent research into the role of CD1 in infectious, autoimmune, allergic and neoplastic disease.

目次

Section 1 - Molecular Biology.- Chapter 1 - Evolutionary Biology of the CD1.- Chapter 2 - Architecture of CD1 Proteins.- Chapter 3 - Structures and Biology of Self Lipid Antigens.- Chapter 4 - Structures and Functions of Microbial Lipid Antigens.- Section 2 - Cellular Biology.- Chapter 5 - CD1 Expression on Antigen Presenting Cells.- Chapter 6 - Pathways of CD1 and Lipid Antigen Delivery, Trafficking, Processing, Loading and Presentation.- Chapter 7 - TCR-Mediated Recognition of Glycolipid CD1 Complexes.- Chapter 8 - Development and Selection of Va14i NKT Cells.- Section 3 - Disease.- Chapter 9 - CD1-Restricted T Cells in Host Defense to Infectious Diseases.- Chapter 10 - NKT Cells and Autoimmune Diseases: Unraveling the Complexity.- Chapter 11 - iNKT Cells in Allergic Disease.- Chapter 12 - CD1-Restricted T Cells and Tumor Immunity.- Chapter 13 - Harnessing NKT Cells for Therapeutic Applications.- Subject index

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA82108330
• ISBN:
  • 9783540695103
• 出版国コード: gw
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Berlin
• ページ数/冊数: vi, 345 p.
• 大きさ: 24 cm
• 分類:
  • SG : 610
• 親書誌ID:
  • BA00773360