MicroRNA methods
著者
書誌事項
MicroRNA methods
(Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 427)
Academic Press, c2007
大学図書館所蔵 全53件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
MicroRNAs (miRNA) are tiny bits of genetic material that were unknown nearly 10 years ago but now represent an exciting field of study in biology. Upon their discovery, researchers revealed for the first time a new mechanism by which microRNA can stop the function of messenger RNA (mRNA) by literally cutting it in half, interfering with the normal function of specific messenger RNAs in gene expression.
This "expression" of genes that code for essential proteins is essentially what controls whether a cell turns into a liver, lung, or brain cell, for example. Understanding what activates this process - or stops it - is a key to understanding the biological process and builds a foundation for advances in medicine and other fields. This volume in Methods in Enzymology presents valuable methods for studying MicroRNA, with three sections covering identification of MicroRNAs and their targets; MicroRNA expression, maturation and functional analysis; and MicroRNAs and disease.
目次
SECTION I. Identifying Micro RNAs and their targets
Chapter 1: Identification of viral miRNAs
Chapter 2: Robust machine learning algorithms predict microRNA genes and targets
Chapter 3: Idenfication of virally encoded microRNAs
Chapter 4: Computational Methods for microRNA Target Prediction
SECTION II. Micro RNA expression, maturation and functional analysis
Chapter 5: In vitro and in vivo assays for the activity of the Drosha-DGCR8 complex
Chapter 6: Microarray analysis of microRNA gene expression.
Chapter 7: Cloning and detecting signature microRNAs from mammalian cells
Chapter 8: Approaches for studying microRNA and small interfering RNA methylation in vitro and in vivo
Chapter 9: Analysis of small RNA profiles during development.
Chapter 10: Dissecting MicroRNA-mediated Gene Regulation and Function in T Cell Development
SECTION III. MiRNAs and Disease
Chapter 11: Investigation of microRNAs alterations in leukemias and lymphomas
Chapter 12: Discovery of pathogen-regulated small RNAs in plants
Chapter 13: Protocols for expression and functional analysis of viral microRNAs
「Nielsen BookData」 より