Penem antibiotics : FCE 22101 and its orally absorbed, ester FCE 22891
Author(s)
Bibliographic Information
Penem antibiotics : FCE 22101 and its orally absorbed, ester FCE 22891
Japan Scientific Societies Press , Springer, 1991
- : Springer, Berlin
- : Springer, New York
- : Japan Scientific Societies Press
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
With an increasing number of microbes becoming immune against the traditional antibiotics, antibiotic research is gaining importance. The penem antibiotics are characterized by a wide antibacterial spectrum and stability against many groups of beta-lactamases. In 1983, the penem FcE 22891, a prodrug, was selected for further development as an antibiotic agent, and it has now been proven a successful therapeutic agent. This text investigates various aspects of the new penem antibiotics including chemical properties and in vitro and in vivo antibacterial activities in both humans and mice.
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