TNF receptor associated factors (TRAFs)
著者
書誌事項
TNF receptor associated factors (TRAFs)
(Advances in experimental medicine and biology, v. 597)
Springer Science+Business Media , Landes Bioscience, c2007
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This book is the only literature that is entirely devoted to TNF Receptor Associated Factors (TRAFs). Almost every aspect of TRAF signaling is covered. The book is intended for a wide audience, including researchers in the field of TRAF signaling and students and postdoctoral fellows learning cell biology and cell signal transduction. This exciting new volume is up-to-date on the most recent advances in TRAF signal transduction.
目次
Phylogeny of the TRAF/MATH Domain.- TRAF1 and Its Biological Functions.- Physiological Roles and Mechanisms of Signaling by TRAF2 and TRAF5.- TRAF3 and Its Biological Function.- TRAF4, the Unique Family Member.- Characteristics and Biological Functions of TRAF6.- Ubiquitination and TRAF signaling.- Structural Revelations of TRAF2 Function in TNF Receptor Signaling Pathway.- Protein-Protein Interactions in TRAF3.- Molecular Basis for the Unique Specificity of TRAF6.- TRAF Proteins in CD40 Signaling.- TRAFs in RANK Signaling.- The LT?R Signaling Pathway.- LMP1 TRAFficking Activates Growth and Survival pathways.- Targeting TRAFs for Therapeutic Intervention.
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